The widely-expressed collagen receptors integrin alpha2beta1 and alpha1beta1 both bind collagen types I-IV (Tulla et al. 2001). Integrin alpha1beta1 binds to collagen type IV and VI with higher affinity than to types I-III, whereas alpha2beta1 has a higher affinity for collagen types I-III than for type IV (Tulla et al. 2001).
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