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UGT1A9 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-400210
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
UDP-glucuronosyltransferase 1-9, UD19_HUMAN
Locations in the PathwayBrowser
Expand all
Drug ADME (Homo sapiens)
Aspirin ADME (Homo sapiens)
UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Homo sapiens)
UGTs (O-GlcA forming) [endoplasmic reticulum membrane] (Homo sapiens)
UGT1A9 [endoplasmic reticulum membrane] (Homo sapiens)
Paracetamol ADME (Homo sapiens)
UGTs glucuronate APAP to APAP-GlcA (Homo sapiens)
UGTs (APAP substrate) [endoplasmic reticulum membrane] (Homo sapiens)
UGT1A9 [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Glucuronidation (Homo sapiens)
Formation of N-glucuronides (Homo sapiens)
UGT1A3,A4,A9 [endoplasmic reticulum membrane] (Homo sapiens)
UGT1A9 [endoplasmic reticulum membrane] (Homo sapiens)
UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Homo sapiens)
UGTs (O-GlcA forming) [endoplasmic reticulum membrane] (Homo sapiens)
UGT1A9 [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of UGT1A9 (Homo sapiens)
UGT1A9 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60656 UGT1A9
Gene Names
UGT1A9, GNT1, UGT1
Chain
signal peptide:1-25, chain:26-530
Reference Genes
BioGPS Gene:54600 UGT1A9
COSMIC (genes):UGT1A9 UGT1A9
CTD Gene:54600 UGT1A9
dbSNP Gene:54600 UGT1A9
ENSEMBL:ENSG00000241119 UGT1A9
ENSEMBL_homo_sapiens_GENE:ENSG00000241119.2 UGT1A9
HGNC:12541 UGT1A9
KEGG Gene (Homo sapiens):54600 UGT1A9
Monarch:54600 UGT1A9
NCBI Gene:54600 UGT1A9
OMIM:191740 UGT1A9
OMIM:606434 UGT1A9
Reference Transcript
RefSeq:NM_021027.2 UGT1A9
Other Identifiers
11718163_a_at
11724282_a_at
11732106_a_at
11741369_a_at
11747457_x_at
11748219_a_at
11750410_a_at
11752269_a_at
204532_PM_x_at
204532_x_at
206094_PM_x_at
206094_x_at
207126_PM_x_at
207126_x_at
208596_PM_s_at
208596_s_at
215125_PM_s_at
215125_s_at
221305_PM_s_at
221305_s_at
2533012
2533013
2533014
2533017
2533021
2533028
2533042
2533050
2533051
2533052
2533053
2533054
2533055
2533056
2533057
2533058
2533059
2533066
2533123
2533124
2533125
2533130
2533131
2533132
32392_s_at
54600
A_14_P126070
A_24_P222872
A_33_P3302075
GE57499
GO:0001889
GO:0001972
GO:0003824
GO:0005783
GO:0005789
GO:0006629
GO:0006805
GO:0008194
GO:0008289
GO:0015020
GO:0016020
GO:0016740
GO:0016757
GO:0019899
GO:0042573
GO:0042803
GO:0043226
GO:0046982
GO:0048856
GO:0051552
GO:0052695
GO:0052696
GO:0052697
HMNXSV003022273
Hs.2056.1.S1_3p_s_at
ILMN_1795872
J04093_s_at
PH_hs_0031610
TC02003895.hg
g13487899_3p_s_at
g9507232_3p_s_at
Participates
as an output of
Expression of UGT1A9 (Homo sapiens)
as a member of
UGTs (APAP substrate) [endoplasmic reticulum membrane] (Homo sapiens)
as a candidate of
UGT1A3,A4,A9 [endoplasmic reticulum membrane] (Homo sapiens)
UGTs (O-GlcA forming) [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
UGT1A6 [endoplasmic reticulum membrane]
(Canis familiaris)
Ugt1a8 [endoplasmic reticulum membrane]
(Mus musculus)
Ugt1a8 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Homologues of UGT1A9 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Homologues of UGT1A9 [endoplasmic reticulum membrane]
(Mus musculus)
Homologues of UGT1A9 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Ugt1a7 [endoplasmic reticulum membrane]
(Mus musculus)
Ugt1a7 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Ugt1a9 [endoplasmic reticulum membrane]
(Mus musculus)
ugt3 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
ugt2 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
UGT1A9 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
UGT1A9 [endoplasmic reticulum membrane]
(Gallus gallus)
Cross References
RefSeq
NP_066307.1
OpenTargets
ENSG00000241119
GeneCards
O60656
HPA
ENSG00000241119-UGT1A9
Ensembl
ENSP00000346768
,
ENST00000354728
,
ENSG00000241119
ZINC target
O60656
PRO
O60656
Pharos - Targets
O60656
HMDB Protein
HMDBP00484
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9HAW7 UGT1A7
1
UGT1A7 [endoplasmic reticulum membrane]
(R-HSA-174927)
0.527
3
UniProt:Q9HAW8 UGT1A10
1
UGT1A10 [endoplasmic reticulum membrane]
(R-HSA-8933307)
0.527
2
UniProt:O60656 UGT1A9
1
UGT1A9 [endoplasmic reticulum membrane]
(R-HSA-400210)
0.471
2
UniProt:P22309 UGT1A1
7
UGT1A1 [endoplasmic reticulum membrane]
(R-HSA-159156)
UGT1A1 S376F [endoplasmic reticulum membrane]
(R-HSA-5604983)
UGT1A1 Q331* [endoplasmic reticulum membrane]
(R-HSA-5605030)
UGT1A1 G309E [endoplasmic reticulum membrane]
(R-HSA-5604963)
UGT1A1 R341* [endoplasmic reticulum membrane]
(R-HSA-5604994)
UGT1A1 Y293Mfs*69 [endoplasmic reticulum membrane]
(R-HSA-5604959)
UGT1A1 L15R [endoplasmic reticulum membrane]
(R-HSA-5604984)
0.471
2
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