Reactome | FADS1 [endoplasmic reticulum membrane]

FADS1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-400122

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Fatty acid desaturase 1, FADS1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60427 FADS1

Gene Names

FADS1, FADSD5

Chain

chain:1-444

Reference Genes

BioGPS Gene:3992 FADS1

COSMIC (genes):FADS1 FADS1

CTD Gene:3992 FADS1

dbSNP Gene:3992 FADS1

ENSEMBL:ENSG00000149485 FADS1

ENSEMBL_homo_sapiens_GENE:ENSG00000149485.19 FADS1

HGNC:3574 FADS1

KEGG Gene (Homo sapiens):3992 FADS1

Monarch:3992 FADS1

NCBI Gene:3992 FADS1

OMIM:606148 FADS1

UCSC:O60427 FADS1

Reference Transcript

RefSeq:NM_013402.4 FADS1

Other Identifiers

11752670_a_at

11755251_x_at

16739132

17118824

208962_PM_s_at

208962_s_at

3375547

3375548

3375549

3375550

3375551

3375552

3375553

3375554

3375559

3375560

3375563

3375564

3375567

3375569

3992

41717_at

41718_g_at

41719_i_at

41720_r_at

7948612

A_23_P203419

GE61115

GO:0000248

GO:0003824

GO:0005739

GO:0005783

GO:0005789

GO:0006351

GO:0006355

GO:0006629

GO:0006631

GO:0006633

GO:0006636

GO:0007267

GO:0008610

GO:0008654

GO:0009267

GO:0016020

GO:0016213

GO:0016491

GO:0016705

GO:0016717

GO:0023052

GO:0030154

GO:0036109

GO:0042759

GO:0043226

GO:0043231

GO:0043651

GO:0044249

GO:0045485

GO:0045595

GO:0046456

GO:0062076

HMNXSV003021918

Hs.132898.0.S2_3p_a_at

Participates

as an output of

Expression of FADS1 (Homo sapiens)

Inferred To

Homologues of FADS1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

fat-3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

fat-4 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

FADS1 [endoplasmic reticulum membrane] (Bos taurus)

FADS1 [endoplasmic reticulum membrane] (Canis familiaris)

FADS1 [endoplasmic reticulum membrane] (Gallus gallus)

FADS1 [endoplasmic reticulum membrane] (Sus scrofa)

fads1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Fads1 [endoplasmic reticulum membrane] (Mus musculus)

Fads1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_037534.3

OpenTargets

ENSG00000149485

ZINC - Substances

FADS1_HUMAN

HPA

ENSG00000149485-FADS1

GeneCards

O60427

ZINC target

O60427

Ensembl

ENSP00000441403, ENST00000433932, ENSG00000149485, ENST00000542506, ENSP00000405087

PRO

O60427

Pharos - Targets

O60427

ZINC - Predictions - Purchasable

FADS1_HUMAN

Orphanet

25431

HMDB Protein

HMDBP02649