Phosphorylation of Plexin-A

Stable Identifier
R-HSA-399934
Type
Reaction
Species
Homo sapiens
Compartment
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Sema3A binding to Neuropilin-1:Plexin-A complex results in conformational change of plexin-A and this conformational change permits Fes nonreceptor tyrosine kinase to bind and phosphorylate Plexin-A. The specific tyrosine residues phosphorylated in the cytoplasmic domain of plexins in response to semaphorin stimulation have not yet been identified.

Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of FES [cytosol]

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