Reactome | RND1 [plasma membrane]

RND1 [plasma membrane]

Stable Identifier

R-HSA-396949

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Rho-related GTP-binding protein Rho6 (Rnd1) , RND1_HUMAN, RHO6

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Locations in the PathwayBrowser for interactor UniProt:O43157 PLXNB1

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RND1 GTPase cycle (Homo sapiens)
        
        RND1 binds GTP (Homo sapiens)
        
        RND1 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q92730 RND1

Gene Names

RND1, RHO6

Chain

chain:1-229, propeptide:230-232

Reference Genes

BioGPS Gene:27289 RND1

COSMIC (genes):RND1 RND1

CTD Gene:27289 RND1

dbSNP Gene:27289 RND1

ENSEMBL:ENSG00000172602 RND1

ENSEMBL_homo_sapiens_GENE:ENSG00000172602.11 RND1

HGNC:18314 RND1

KEGG Gene (Homo sapiens):27289 RND1

Monarch:27289 RND1

NCBI Gene:27289 RND1

OMIM:609038 RND1

UCSC:Q92730 RND1

Reference Transcript

RefSeq:NM_014470.3 RND1

Other Identifiers

11732233_a_at

11732234_a_at

16764053

210056_PM_at

210056_at

27289

3453349

3453350

3453351

3453352

3453354

3453355

3453359

3453361

3453362

37785_at

7962884

A_23_P53370

GE62482

GO:0000166

GO:0003824

GO:0003924

GO:0005102

GO:0005515

GO:0005525

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005912

GO:0007010

GO:0007015

GO:0007155

GO:0007162

GO:0007165

GO:0007264

GO:0015629

GO:0016020

GO:0016322

GO:0016477

GO:0016787

GO:0019901

GO:0023052

GO:0030154

GO:0043226

GO:0043231

GO:0048856

GO:0048870

HMNXSV003016407

Hs.124940.0.S2_3p_at

ILMN_1651838

PH_hs_0007040

TC12001459.hg

Participates

as an input of

RND1 binds GTP (Homo sapiens)

as a component of

Inferred To

Homologues of RND1 [plasma membrane] (Saccharomyces cerevisiae)

Homologues of RND1 [plasma membrane] (Schizosaccharomyces pombe)

Rnd1 [plasma membrane] (Rattus norvegicus)

RND1 [plasma membrane] (Bos taurus)

RND1 [plasma membrane] (Canis familiaris)

RND1 [plasma membrane] (Gallus gallus)

RND1 [plasma membrane] (Mus musculus)

RND1 [plasma membrane] (Saccharomyces cerevisiae)

RND1 [plasma membrane] (Schizosaccharomyces pombe)

RND1 [plasma membrane] (Sus scrofa)

rnd1 [plasma membrane] (Xenopus tropicalis)

Ghost homologue of RND1 [plasma membrane] (Caenorhabditis elegans)

Ghost homologue of RND1 [plasma membrane] (Drosophila melanogaster)

rnd1b [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_055285.1

OpenTargets

ENSG00000172602

GeneCards

Q92730

HPA

ENSG00000172602-RND1

Ensembl

ENSG00000172602, ENSP00000308461, ENST00000309739

PRO

Q92730

Pharos - Targets

Q92730

PDB

3Q3J, 2CLS, 2REX

HMDB Protein

HMDBP02857

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43157 PLXNB1	2	PLXNB1 [plasma membrane] (R-HSA-3008951) p-Y-PLXNB1 [plasma membrane] (R-HSA-419609)	0.775	5
UniProt:Q14451 GRB7	1	GRB7 [cytosol] (R-HSA-204819)	0.581	4
UniProt:O15031 PLXB2			0.558	2
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:P53365 ARFIP2	1	ARFIP2 [cytosol] (R-HSA-6813848)	0.556	3