Thrombin-activated PARs binds G-protein G12/13

Stable Identifier
R-HSA-396941
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Thrombin-activated PARs binds G-protein G12/13
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Thrombin receptors activate G-proteins in the G12/13 family. Gq knockout mice exhibit defective platelet activation, but retain shape change responses to thrombin, mediated by G12/13.

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Inferred From
Thrombin-activated PAR binds G-protein G12/13 (Mus musculus)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2009-03-10)
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