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G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane]
Stable Identifier
R-HSA-396910
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
GABA receptor activation (Homo sapiens)
GABA B receptor activation (Homo sapiens)
Activation of GABAB receptors (Homo sapiens)
Adenylate cyclase inhibitory pathway (Homo sapiens)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
Adenylate cyclase inhibitory pathway (Homo sapiens)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (i) inhibits adenylate cyclase (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Homo sapiens)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (z) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
Participants
components
Adenylate cyclase (Mg2+ cofactor) [plasma membrane] (Homo sapiens)
G alpha (i): GTP [plasma membrane] (Homo sapiens)
Participant Of
output
G alpha (i) inhibits adenylate cyclase
input
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex
hasComponent
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane]
This entity regulates
Negatively
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate
Inferred To
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Caenorhabditis elegans)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Canis familiaris)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Danio rerio)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Dictyostelium discoideum)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Drosophila melanogaster)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Gallus gallus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Mus musculus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Rattus norvegicus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Sus scrofa)
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