Reactome | EPHB3 (34-?) [extracellular region]

EPHB3 (34-?) [extracellular region]

Stable Identifier

R-HSA-3928460

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Ephrin type-B receptor 3 ecNumber2.7.10.1/ecNumber, EPHB3_HUMAN, EPHB3

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - EPH-Ephrin signaling (Homo sapiens)
      - EPH-ephrin mediated repulsion of cells (Homo sapiens)
        
        MMP2,9 cleave EPHB (Homo sapiens)
        
        EPHB N-terminal fragments [extracellular region] (Homo sapiens)
        
        EPHB3 (34-?) [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:P54753 EPHB3

Gene Names

EPHB3, ETK2, HEK2, TYRO6

Chain

signal peptide:1-33, chain:34-998

Reference Genes

BioGPS Gene:2049 EPHB3

COSMIC (genes):EPHB3 EPHB3

CTD Gene:2049 EPHB3

dbSNP Gene:2049 EPHB3

ENSEMBL:ENSG00000182580 EPHB3

HGNC:3394 EPHB3

KEGG Gene (Homo sapiens):2049 EPHB3

Monarch:2049 EPHB3

NCBI Gene:2049 EPHB3

OMIM:601839 EPHB3

UCSC:P54753 EPHB3

Reference Transcript

RefSeq:NM_004443.3 EPHB3

Other Identifiers

0001740128

11724421_at

1438_at

16949062

204600_at

2049

2655876

2655877

2655880

2655883

2655884

2655890

2655892

2655893

2655895

2655896

2655898

2655899

2655901

2655902

2655904

2655907

2655908

2655909

2655910

2655912

8084524

A_14_P130352

A_14_P202445

A_23_P95060

GE59998

GO:0000166

GO:0000902

GO:0001525

GO:0001655

GO:0002376

GO:0003674

GO:0004672

GO:0004713

GO:0004714

GO:0005003

GO:0005005

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005622

GO:0005737

GO:0005829

GO:0005886

GO:0005887

GO:0006464

GO:0006468

GO:0007155

GO:0007165

GO:0007169

GO:0007275

GO:0007399

GO:0007411

GO:0007413

GO:0008046

GO:0008150

GO:0016020

GO:0016021

GO:0016301

GO:0016310

GO:0016477

GO:0016740

GO:0018108

GO:0021952

GO:0022038

GO:0022407

GO:0022607

GO:0030154

GO:0030425

GO:0031290

GO:0032991

GO:0033674

GO:0034330

GO:0034446

GO:0040011

GO:0042995

GO:0043005

GO:0043087

GO:0043167

GO:0043235

GO:0046777

GO:0048013

GO:0048538

GO:0048546

GO:0048646

GO:0048856

GO:0048870

GO:0050770

GO:0051965

GO:0060021

GO:0060996

GO:0060997

ILMN_1741346

PH_hs_0000371

TC03001007.hg

X75208_at

X75208cds_3p_s_at

g4758287_3p_at

g4758287_3p_x_at

Participant Of

hasMember

EPHB N-terminal fragments [extracellular region]

Other forms of this molecule

EPHB3 (?-?) [plasma membrane]

EPHB3 (?-998) [cytosol]

EPHB3 (?-998) [plasma membrane]

EPHB3 [plasma membrane]

p-Y608,Y614-EPHB3 [plasma membrane]

Inferred To

Eph [extracellular region] (Drosophila melanogaster)

Ephb3 [extracellular region] (Mus musculus)

Ephb3 [extracellular region] (Rattus norvegicus)

ephb3 [extracellular region] (Xenopus tropicalis)

EPHB3 (34-?) [extracellular region] (Bos taurus)

EPHB3 (34-?) [extracellular region] (Danio rerio)

EPHB3 (34-?) [extracellular region] (Gallus gallus)

EPHB3 (34-?) [extracellular region] (Sus scrofa)

EPHB3 [extracellular region] (Canis familiaris)

vab-1 [extracellular region] (Caenorhabditis elegans)

Cross References

RefSeq

NP_004434.2

ZINC - World Drugs

EPHB3_HUMAN

OpenTargets

ENSG00000182580

ZINC - FDA approved

EPHB3_HUMAN

ZINC - Substances

EPHB3_HUMAN

ZINC target

P54753

PRO

P54753

PDB

5L6O, 3P1I, 5L6P, 3ZFY

ZINC - Investigational

EPHB3_HUMAN

GeneCards

P54753

HPA

ENSG00000182580-EPHB3

Ensembl

ENSP00000332118, ENST00000330394, ENSG00000182580

ZINC - Predictions - Purchasable

EPHB3_HUMAN

HMDB Protein

HMDBP01507