SUMOylation of CREBBP with SUMO1

Stable Identifier
R-HSA-3927959
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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As inferred from mouse homologs, CREBBP (CBP) is SUMOylated at lysine-998, lysine-1033, and lysine-1056 with SUMO1. SUMOylation recruits DAXX and HDAC2 to repress transcription.

Participants
Participates
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [cytoplasm]

Inferred From
Authored
Reviewed
Created
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