SUMOylation of CREBBP with SUMO1

Stable Identifier
R-HSA-3927959
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As inferred from mouse homologs, CREBBP (CBP) is SUMOylated at lysine-998, lysine-1033, and lysine-1056 with SUMO1. SUMOylation recruits DAXX and HDAC2 to repress transcription.
Participants
Participates
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]

Inferred From
Authored
Reviewed
Created
Cite Us!