SUMOylation of CREBBP with SUMO1

Stable Identifier
R-HSA-3927959
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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SUMOylation of CREBBP with SUMO1
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As inferred from mouse homologs, CREBBP (CBP) is SUMOylated at lysine-998, lysine-1033, and lysine-1056 with SUMO1. SUMOylation recruits DAXX and HDAC2 to repress transcription.

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Output
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as an event of
Catalyst Activity

SUMO transferase activity of SUMO1:C93-UBE2I [cytoplasm]

Physical Entity
SUMO1:C93-UBE2I [nucleoplasm] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Inferred From
Sumoylation of Crebbp with Sumo1 (Mus musculus)
Authored
May, B  (2013-07-17)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-07-21)
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