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TUBB1 folding intermediate [cytosol]
Stable Identifier
R-HSA-392793
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
beta tubulin 1 folding intermediate
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding (Homo sapiens)
Formation of tubulin folding intermediates by CCT/TriC (Homo sapiens)
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)
tubulin-GTP folding intermediate [cytosol] (Homo sapiens)
alpha/beta tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
Post-chaperonin tubulin folding pathway (Homo sapiens)
Beta-tubulin:GTP + Cofactor A -> Beta-tubulin:GTP: Cofactor A (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
cofactor A:GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
Beta-tubulin:GTP: Cofactor A+ Cofactor D -> Beta-tubulin:GTP:Cofactor D + Cofactor A (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
cofactor A:GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
Beta-tubulin:GTP:Cofactor D+alpha-tubulin:GTP:Cofactor E-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
beta tubulin:GTP: Cofactor D:alpha tubulin:GTP:Cofactor E [cytosol] (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E+ Cofactor C-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C (Homo sapiens)
beta tubulin:GTP: Cofactor D:alpha tubulin:GTP:Cofactor E [cytosol] (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E : Cofactor C [cytosol] (Homo sapiens)
beta tubulin:GTP: Cofactor D:alpha tubulin:GTP:Cofactor E [cytosol] (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi (Homo sapiens)
beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E : Cofactor C [cytosol] (Homo sapiens)
beta tubulin:GTP: Cofactor D:alpha tubulin:GTP:Cofactor E [cytosol] (Homo sapiens)
Cofactor D:GTP:beta tubulin [cytosol] (Homo sapiens)
GTP:beta-tubulin folding intermediate [cytosol] (Homo sapiens)
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
TUBB1 folding intermediate [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H4B7 TUBB1
Gene Names
TUBB1
Chain
chain:1-451
Reference Genes
BioGPS Gene:81027 TUBB1
COSMIC (genes):TUBB1 TUBB1
CTD Gene:81027 TUBB1
dbSNP Gene:81027 TUBB1
ENSEMBL:ENSG00000101162 TUBB1
ENSEMBL:ENSG00000101162.4 TUBB1
HGNC:16257 TUBB1
KEGG Gene (Homo sapiens):81027 TUBB1
Monarch:81027 TUBB1
NCBI Gene:81027 TUBB1
OMIM:612901 TUBB1
UCSC:Q9H4B7 TUBB1
Reference Transcript
RefSeq:NM_030773.3 TUBB1
Other Identifiers
11725897_at
16915395
208601_PM_s_at
208601_s_at
230690_PM_at
230690_at
3891343
3891344
3891345
3891346
3891348
3891349
3891350
3891351
48085_at
8063716
81027
A_14_P103140
A_23_P6034
A_24_P228550
GE543157
GO:0000166
GO:0000226
GO:0000278
GO:0002376
GO:0003824
GO:0003924
GO:0005198
GO:0005200
GO:0005525
GO:0005576
GO:0005615
GO:0005737
GO:0005856
GO:0005874
GO:0007010
GO:0007017
GO:0007155
GO:0015630
GO:0016787
GO:0030154
GO:0030220
GO:0030878
GO:0042060
GO:0043226
GO:0045171
GO:0046785
GO:0046872
GO:0048856
GO:0051225
GO:0065003
GO:0070062
GO:0070327
GO:0070527
GO:0072686
HMNXSV003021293
Hs.303023.1.A1_3p_at
ILMN_1710280
PH_hs_0015644
TC20000468.hg
g13562113_3p_s_at
Participates
as a member of
beta-tubulin folding intermediate [cytosol] (Homo sapiens)
Other forms of this molecule
TUBB1 unfolded [cytosol]
Polyglycyl-TUBB1 [cytosol]
Polyglutamyl-TUBB1 [cytosol]
TUBB1 [axonemal microtubule]
TUBB1 [cytosol]
Cross References
RefSeq
NP_110400.1
OpenTargets
ENSG00000101162
ZINC - Substances
TBB1_HUMAN
ZINC target
Q9H4B7
ZINC - Biogenic
TBB1_HUMAN
PRO
Q9H4B7
HPA
ENSG00000101162-TUBB1
GeneCards
Q9H4B7
Ensembl
ENSP00000217133
,
ENSG00000101162
,
ENST00000217133
Pharos - Targets
Q9H4B7
ZINC - Predictions - Purchasable
TBB1_HUMAN
Orphanet
20427
HMDB Protein
HMDBP08601
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.527
2
UniProt:O75161 NPHP4
1
NPHP4 [cytosol]
(R-HSA-2059925)
0.508
3
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