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RAP1GAP2 [cytosol]
Stable Identifier
R-HSA-392491
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rap1 GTPase-activating protein 2, RPGP2_HUMAN, GARNL4
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Rap1 signalling (Homo sapiens)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Homo sapiens)
RAP1GAP2 [cytosol] (Homo sapiens)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Homo sapiens)
RAP1GAP2 [cytosol] (Homo sapiens)
PKA/PKG phosphorylate Rap1GAP2 (Homo sapiens)
RAP1GAP2 [cytosol] (Homo sapiens)
Rap1 signal termination by Rap1GAPs (Homo sapiens)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Homo sapiens)
RAP1GAP2 [cytosol] (Homo sapiens)
Rap1 GTPase-activating proteins [cytosol] (Homo sapiens)
RAP1GAP2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q684P5 RAP1GAP2
Gene Names
RAP1GAP2, GARNL4, KIAA1039, RAP1GA2
Chain
chain:1-730
Reference Genes
BioGPS Gene:23108 RAP1GAP2
COSMIC (genes):RAP1GAP2 RAP1GAP2
CTD Gene:23108 RAP1GAP2
dbSNP Gene:23108 RAP1GAP2
ENSEMBL:ENSG00000132359 RAP1GAP2
HGNC:29176 RAP1GAP2
Monarch:23108 RAP1GAP2
NCBI Gene:23108 RAP1GAP2
OMIM:618714 RAP1GAP2
UCSC:Q684P5 RAP1GAP2
Reference Transcript
RefSeq:XM_017024370.1 RAP1GAP2
RefSeq:NM_001100398.1 RAP1GAP2
RefSeq:NM_001330058.1 RAP1GAP2
RefSeq:NM_015085.4 RAP1GAP2
RefSeq:XM_011523741.2 RAP1GAP2
Other Identifiers
11721420_a_at
11721421_s_at
11749458_a_at
11749459_a_at
16829690
213280_PM_at
213280_at
23108
3706447
3706452
3706453
3706454
3706464
3706465
3706466
3706479
3706493
3706503
3706504
3706508
3706509
3706510
3706515
3706517
3706519
3706521
3706522
3706523
3706527
3706528
3706529
3706530
3706531
3706533
3706534
3706535
3706536
3706537
3706539
3706540
3706541
3706542
3706543
3706544
3706545
3706546
3706547
3706548
3706549
3706550
3706551
3706552
3706553
3706554
3706555
3706556
3706557
37517_at
73108_at
8003773
A_14_P103525
A_21_P0011508
A_23_P412214
A_24_P911927
A_33_P3333146
GE53709
GO:0002250
GO:0002376
GO:0005096
GO:0005515
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005886
GO:0008361
GO:0031965
GO:0048471
GO:0051056
GO:0098772
HMNXSV003000545
Hs.301552.0.S1_3p_at
Hs.301552.0.S1_3p_x_at
ILMN_1666832
ILMN_1690042
ILMN_1732830
PH_hs_0026529
PH_hs_0033949
TC17000026.hg
TC17002013.hg
Participates
as a member of
Rap1 GTPase-activating proteins [cytosol] (Homo sapiens)
as a component of
RAP1GAP2:14-3-3beta, zeta [cytosol] (Homo sapiens)
as an input of
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Homo sapiens)
PKA/PKG phosphorylate Rap1GAP2 (Homo sapiens)
Other forms of this molecule
p-S7-RAP1GAP2 [cytosol]
Inferred To
rap1gap2 [cytosol]
(Xenopus tropicalis)
rapgap1 [cytosol]
(Dictyostelium discoideum)
rapgapB [cytosol]
(Dictyostelium discoideum)
RAP1GAP2 [cytosol]
(Bos taurus)
RAP1GAP2 [cytosol]
(Caenorhabditis elegans)
RAP1GAP2 [cytosol]
(Canis familiaris)
RAP1GAP2 [cytosol]
(Dictyostelium discoideum)
RAP1GAP2 [cytosol]
(Gallus gallus)
RAP1GAP2 [cytosol]
(Sus scrofa)
Homologues of RAP1GAP2 [cytosol]
(Dictyostelium discoideum)
Rap1gap2 [cytosol]
(Mus musculus)
Rap1gap2 [cytosol]
(Rattus norvegicus)
rap1gap2b [cytosol]
(Danio rerio)
RapGAP1 [cytosol]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENSP00000254695
,
ENSP00000439688
,
ENSP00000389824
,
ENST00000254695
,
ENST00000366401
,
ENST00000540393
OpenTargets
ENSG00000132359
HPA
ENSG00000132359-RAP1GAP2
PRO
Q684P5
Pharos - Targets
Q684P5
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:P47736 RAP1GAP
1
RAP1GAP [cytosol]
(R-HSA-392493)
0.499
2
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