Biochemical and cellular studies have shown that the p101/p110 form of PI3K gamma is substantially activated by G beta:gamma in a manner that is dependent on p101.
Stoyanov, B, Volinia, S, Hanck, T, Rubio, I, Loubtchenkov, M, Malek, D, Stoyanova, S, Vanhaesebroeck, B, Dhand, R, Nurnberg, B
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