Gbeta:gamma recruits PI3K gamma

Stable Identifier
R-HSA-392295
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Gbeta:gamma recruits PI3K gamma
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
G beta:gamma recruits PI3K gamma from the cytosol to the plasma membrane by interacting with the p101 regulatory subunit. G beta:gamma activates PI3Kgamma via interactions with the catalytic p110 subunit.
Literature References
PubMed ID Title Journal Year
12507995 Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma

Schultz, G, Brock, C, Michalke, M, Spicher, K, Nurnberg, B, Reusch, HP, Czupalla, C, Schaefer, M

J Cell Biol 2003
Participants
Input
Output
Participates
as an event of
Orthologous Events
Gbeta:gamma recruits PI3K gamma (Bos taurus)
Gbeta:gamma recruits PI3K gamma (Canis familiaris)
Gbeta:gamma recruits PI3K gamma (Gallus gallus)
Gbeta:gamma recruits PI3K gamma (Mus musculus)
Gbeta:gamma recruits PI3K gamma (Sus scrofa)
Authored
Jupe, S  (2009-03-02)
Reviewed
Akkerman, JW  (2009-06-03)
Created
Jupe, S  (2009-03-02)
Cite Us!