Gbeta:gamma recruits PI3K gamma

Stable Identifier
R-HSA-392295
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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G beta:gamma recruits PI3K gamma from the cytosol to the plasma membrane by interacting with the p101 regulatory subunit. G beta:gamma activates PI3Kgamma via interactions with the catalytic p110 subunit.

Literature References
PubMed ID Title Journal Year
12507995 Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma

Brock, C, Schaefer, M, Reusch, HP, Czupalla, C, Michalke, M, Spicher, K, Schultz, G, Nurnberg, B

J Cell Biol 2003
Participants
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Orthologous Events
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