Gbeta:gamma recruits PI3K gamma

Stable Identifier
R-HSA-392295
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Gbeta:gamma recruits PI3K gamma
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G beta:gamma recruits PI3K gamma from the cytosol to the plasma membrane by interacting with the p101 regulatory subunit. G beta:gamma activates PI3Kgamma via interactions with the catalytic p110 subunit.

Literature References
PubMed ID Title Journal Year
12507995 Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma

Schultz, G, Brock, C, Michalke, M, Spicher, K, Nurnberg, B, Reusch, HP, Czupalla, C, Schaefer, M

J Cell Biol 2003
Participants
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Output
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as an event of
Orthologous Events
Gbeta:gamma recruits PI3K gamma (Bos taurus)
Gbeta:gamma recruits PI3K gamma (Canis familiaris)
Gbeta:gamma recruits PI3K gamma (Danio rerio)
Gbeta:gamma recruits PI3K gamma (Gallus gallus)
Gbeta:gamma recruits PI3K gamma (Mus musculus)
Gbeta:gamma recruits PI3K gamma (Sus scrofa)
Gbeta:gamma recruits PI3K gamma (Xenopus tropicalis)
Authored
Jupe, S  (2009-03-02)
Reviewed
Akkerman, JW  (2009-06-03)
Created
Jupe, S  (2009-03-02)
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