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GRIA4 [plasma membrane]
Stable Identifier
R-HSA-392229
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
GluR4
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
SALM2 associate with AMPA and NMDA receptors (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
SALM2:AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Unblocking of GRIN1:GRIN2 NMDA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
Activation of AMPA receptors (Homo sapiens)
Activation of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Activation of Ca permeable AMPA receptors (Homo sapiens)
Ca permeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptor ligand binding (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptor ligand binding (Homo sapiens)
Ca permeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of AMPA receptors (Homo sapiens)
Trafficking of GluR1-containing AMPA receptors (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors (Homo sapiens)
Endocytosis of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptors (with phospho GluR2 S880) [plasma membrane] (Homo sapiens)
AMPA receptors (heteromers) with phopho GluR2 [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to synapse (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48058 GRIA4
Gene Names
GRIA4, GLUR4
Chain
signal peptide:1-20, chain:21-902
Reference Genes
BioGPS Gene:2893 GRIA4
COSMIC (genes):GRIA4 GRIA4
CTD Gene:2893 GRIA4
dbSNP Gene:2893 GRIA4
ENSEMBL:ENSG00000152578 GRIA4
HGNC:4574 GRIA4
KEGG Gene (Homo sapiens):2893 GRIA4
Monarch:2893 GRIA4
NCBI Gene:2893 GRIA4
OMIM:138246 GRIA4
UCSC:P48058 GRIA4
Reference Transcript
RefSeq:NM_001112812.1 GRIA4
RefSeq:NM_001077244.1 GRIA4
RefSeq:NM_001077243.2 GRIA4
RefSeq:XM_006718823.1 GRIA4
RefSeq:NM_000829.3 GRIA4
Other Identifiers
0003290603
11730475_a_at
11730562_a_at
16730706
208464_at
238663_x_at
2893
3347121
3347122
3347123
3347124
3347125
3347126
3347127
3347128
3347129
3347130
3347150
3347151
3347163
3347167
3347168
3347169
3347170
3347171
3347172
3347173
3347175
3347176
3347177
3347178
3347179
3347182
3347183
3347194
3347195
3347198
3347199
59753_r_at
73453_at
78372_at
7943530
A_14_P100193
A_23_P98369
A_33_P3217153
A_33_P3497352
GE535280
GO:0001540
GO:0003674
GO:0004970
GO:0004971
GO:0005216
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005886
GO:0006810
GO:0006811
GO:0007165
GO:0007215
GO:0007267
GO:0007268
GO:0008150
GO:0015276
GO:0016020
GO:0016021
GO:0022857
GO:0030054
GO:0030425
GO:0030666
GO:0031410
GO:0032281
GO:0032991
GO:0034220
GO:0035235
GO:0038023
GO:0042995
GO:0043025
GO:0043197
GO:0043226
GO:0045202
GO:0045211
GO:0055085
GO:1903561
GO:2000310
HMNXSV003036348
HMNXSV003051853
Hs.31677.0.S1_3p_at
Hs.31677.0.S1_3p_x_at
ILMN_1692094
ILMN_1863253
ILMN_2322100
PH_hs_0022305
PH_hs_0039840
TC11000968.hg
U16129_at
g4557630_3p_at
Participates
as a member of
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
Other forms of this molecule
GRIA4 [endocytic vesicle membrane]
Inferred To
glr-4 [plasma membrane]
(Caenorhabditis elegans)
GluRIIA [plasma membrane]
(Drosophila melanogaster)
glr-1 [plasma membrane]
(Caenorhabditis elegans)
glr-7 [plasma membrane]
(Caenorhabditis elegans)
Ir21a [plasma membrane]
(Drosophila melanogaster)
Ir75d [plasma membrane]
(Drosophila melanogaster)
GluRIID [plasma membrane]
(Drosophila melanogaster)
Ir75a [plasma membrane]
(Drosophila melanogaster)
GluRIA [plasma membrane]
(Drosophila melanogaster)
GluRIIC [plasma membrane]
(Drosophila melanogaster)
gria4b [plasma membrane]
(Danio rerio)
Homologues of GRIA4 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GRIA4 [plasma membrane]
(Danio rerio)
Homologues of GRIA4 [plasma membrane]
(Drosophila melanogaster)
glr-5 [plasma membrane]
(Caenorhabditis elegans)
KaiR1D [plasma membrane]
(Drosophila melanogaster)
glr-2 [plasma membrane]
(Caenorhabditis elegans)
Ir75c [plasma membrane]
(Drosophila melanogaster)
Ir84a [plasma membrane]
(Drosophila melanogaster)
GluRIIE [plasma membrane]
(Drosophila melanogaster)
GluRIIB [plasma membrane]
(Drosophila melanogaster)
Ir25a [plasma membrane]
(Drosophila melanogaster)
GRIA4 [plasma membrane]
(Canis familiaris)
GRIA4 [plasma membrane]
(Gallus gallus)
GRIA4 [plasma membrane]
(Sus scrofa)
Gria4 [plasma membrane]
(Mus musculus)
Gria4 [plasma membrane]
(Rattus norvegicus)
Ir64a [plasma membrane]
(Drosophila melanogaster)
glr-6 [plasma membrane]
(Caenorhabditis elegans)
glr-3 [plasma membrane]
(Caenorhabditis elegans)
gria4a [plasma membrane]
(Danio rerio)
GluRIB [plasma membrane]
(Drosophila melanogaster)
Ir93a [plasma membrane]
(Drosophila melanogaster)
Ir76b [plasma membrane]
(Drosophila melanogaster)
Ir8a [plasma membrane]
(Drosophila melanogaster)
clumsy [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001070711.2
,
NP_001070712.1
,
XP_006718886.1
,
NP_000820.3
,
NP_001106283.1
Guide to Pharmacology - Targets
447
OpenTargets
ENSG00000152578
HPA
ENSG00000152578-GRIA4
GeneCards
P48058
Ensembl
ENST00000530497
,
ENSP00000376833
,
ENST00000282499
,
ENSP00000415551
,
ENSG00000152578
,
ENST00000393125
,
ENSP00000435775
,
ENSP00000282499
,
ENST00000428631
ZINC target
P48058
PRO
P48058
Pharos - Targets
P48058
GlyGen
P48058
Orphanet
28743
HMDB Protein
HMDBP12051
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