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GRIA4 [plasma membrane]
Stable Identifier
R-HSA-392229
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
GluR4
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
SALM2 associate with AMPA and NMDA receptors (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
SALM2:AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Unblocking of GRIN1:GRIN2 NMDA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
Activation of AMPA receptors (Homo sapiens)
Activation of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Activation of Ca permeable AMPA receptors (Homo sapiens)
Ca permeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptor ligand binding (Homo sapiens)
Ca impermeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptor ligand binding (Homo sapiens)
Ca permeable AMPA receptor ligand complex [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of AMPA receptors (Homo sapiens)
Trafficking of GluR1-containing AMPA receptors (Homo sapiens)
Ca permeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR1 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors (Homo sapiens)
Endocytosis of Ca impermeable AMPA receptors (Homo sapiens)
Ca impermeable AMPA receptors (with phospho GluR2 S880) [plasma membrane] (Homo sapiens)
AMPA receptors (heteromers) with phopho GluR2 [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to synapse (Homo sapiens)
Ca impermeable AMPA receptors [plasma membrane] (Homo sapiens)
AMPA receptors containing GluR2 (heteromers) [plasma membrane] (Homo sapiens)
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
GRIA4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P48058 GRIA4
Gene Names
GRIA4, GLUR4, GLUR4
Chain
signal peptide:1-20, chain:21-902
Reference Genes
BioGPS Gene:2893 P480582
COSMIC (genes):GRIA4 GRIA4
CTD Gene:2893 P480582
dbSNP Gene:2893 P480582
ENSEMBL:ENSG00000152578 GRIA4
HGNC:4574 P480582
KEGG:hsa:2893 P480582
Monarch:2893 P480582
NCBI Gene:2893 P480582
OMIM:138246 P480582
UCSC:P48058 P480582
Reference Transcript
RefSeq:NM_001077243.2 P480582
RefSeq:NM_001112812.1 P480582
RefSeq:XM_006718823.1 P480582
RefSeq:NM_000829.3 P480582
RefSeq:NM_001077244.1 P480582
Participates
as a member of
GRIA3,GRIA4 [plasma membrane] (Homo sapiens)
Other forms of this molecule
GRIA4 [endocytic vesicle membrane]
Inferred To
GluRIA [plasma membrane]
(Drosophila melanogaster)
glr-4 [plasma membrane]
(Caenorhabditis elegans)
glr-1 [plasma membrane]
(Caenorhabditis elegans)
GluRIB [plasma membrane]
(Drosophila melanogaster)
Homologues of GRIA4 [plasma membrane]
(Caenorhabditis elegans)
Homologues of GRIA4 [plasma membrane]
(Drosophila melanogaster)
Ir21a [plasma membrane]
(Drosophila melanogaster)
Ir93a [plasma membrane]
(Drosophila melanogaster)
Ir76b [plasma membrane]
(Drosophila melanogaster)
glr-2 [plasma membrane]
(Caenorhabditis elegans)
Ir25a [plasma membrane]
(Drosophila melanogaster)
GRIA4 [plasma membrane]
(Caenorhabditis elegans)
GRIA4 [plasma membrane]
(Canis familiaris)
GRIA4 [plasma membrane]
(Danio rerio)
GRIA4 [plasma membrane]
(Drosophila melanogaster)
GRIA4 [plasma membrane]
(Gallus gallus)
GRIA4 [plasma membrane]
(Mus musculus)
GRIA4 [plasma membrane]
(Rattus norvegicus)
GRIA4 [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
447
ENSEMBL
ENSP00000435775
,
ENST00000282499
,
ENSP00000282499
,
ENST00000393125
,
ENST00000530497
,
ENSP00000415551
,
ENST00000428631
,
ENSP00000376833
,
ENSG00000152578
OpenTargets
ENSG00000152578
GeneCards
GRIA4
HPA
ENSG00000152578-GRIA4
ZINC target
P48058
PRO
P48058
Pharos - Targets
P48058
GlyGen
P48058
Orphanet
GRIA4
HMDB Protein
HMDBP12051
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