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GUCY1A3 [cytosol]
Stable Identifier
R-HSA-391998
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Guanylate cyclase soluble subunit alpha-3, GCYA3_HUMAN
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Nitric oxide stimulates guanylate cyclase (Homo sapiens)
NO binds to Guanylate Cyclase (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)
Guanylate cyclase:CO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Muscle contraction (Homo sapiens)
Smooth Muscle Contraction (Homo sapiens)
Cinaciguat binds sGC:NO (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO binds to Guanylate Cyclase (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Soluble guanylate cyclase converts GTP to cGMP (Homo sapiens)
Guanylate cyclase:CO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO:sGC:cinaciguat [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
sGC stimulators bind sGC:NO (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
NO:sGC:sGC stimulators [cytosol] (Homo sapiens)
Guanylate cyclase:NO [cytosol] (Homo sapiens)
Guanylate cyclase, soluble [cytosol] (Homo sapiens)
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
GUCY1A3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02108 GUCY1A3
Gene Names
GUCY1A3, GUC1A3, GUCSA3, GUCY1A1
Chain
chain:1-690
Reference Genes
BioGPS Gene:2982 GUCY1A3
COSMIC (genes):GUCY1A1 GUCY1A3
CTD Gene:2982 GUCY1A3
dbSNP Gene:2982 GUCY1A3
ENSEMBL:ENSG00000164116 GUCY1A3
HGNC:4685 GUCY1A3
Monarch:2982 GUCY1A3
NCBI Gene:2982 GUCY1A3
OMIM:139396 GUCY1A3
UCSC:Q02108 GUCY1A3
Reference Transcript
RefSeq:NM_001130682.2 GUCY1A3
RefSeq:NM_000856.5 GUCY1A3
RefSeq:XM_006714196.2 GUCY1A3
RefSeq:NM_001256449.1 GUCY1A3
RefSeq:NM_001130687.2 GUCY1A3
RefSeq:XM_006714197.2 GUCY1A3
RefSeq:NM_001130684.2 GUCY1A3
RefSeq:XM_005262955.2 GUCY1A3
RefSeq:NM_001130683.3 GUCY1A3
Other Identifiers
11722136_at
11722137_a_at
11722138_s_at
11722139_at
11722140_a_at
11735471_a_at
11739830_a_at
11741088_a_at
11749919_a_at
11758520_s_at
16971712
221942_PM_s_at
221942_s_at
227235_PM_at
227235_at
229530_PM_at
229530_at
239580_PM_at
239580_at
2748831
2748832
2748833
2748834
2748835
2748836
2748837
2748850
2748851
2748852
2748853
2748858
2748860
2748862
2748863
2748864
2748865
2748866
2748867
2748873
2748874
2748879
2748885
2748886
2748887
2748888
2748889
2748890
2748891
2748893
2748894
2748896
2748897
2748898
2748899
2748900
2748901
2748902
2748903
2982
36918_at
42999_at
48340_at
57486_r_at
57487_at
77045_at
8097957
89394_at
A_23_P69573
A_32_P179138
A_33_P3269109
A_33_P3269110
GE514839
GE60325
GE828965
GO:0003012
GO:0003013
GO:0003824
GO:0004383
GO:0005515
GO:0005525
GO:0005737
GO:0005829
GO:0006182
GO:0007263
GO:0008015
GO:0008074
GO:0008217
GO:0009190
GO:0009975
GO:0010750
GO:0016829
GO:0016849
GO:0019934
GO:0020037
GO:0023052
GO:0035556
GO:0038023
GO:0038060
GO:0055086
GO:0060087
GO:0060089
GO:0070482
GO:0098925
GO:0098978
GO:0098982
GO:1901135
HMNXSV003021392
HMNXSV003041660
HMNXSV003044776
Hs.143691.0.A1_3p_at
Hs.22247.0.A1_3p_at
Hs.306079.1.A1_3p_s_at
Hs.9094.0.A1_3p_at
ILMN_1808590
ILMN_2131177
PH_hs_0001945
PH_hs_0025285
TC04000787.hg
TC04002283.hg
X66534_at
Participates
as a member of
Guanylate cyclase soluble subunit alpha [cytosol] (Homo sapiens)
Inferred To
gucy1a1 [cytosol]
(Danio rerio)
GUCY1A1 [cytosol]
(Bos taurus)
GUCY1A1 [cytosol]
(Canis familiaris)
GUCY1A1 [cytosol]
(Sus scrofa)
GUCY1A3 [cytosol]
(Gallus gallus)
Gycalpha99B [cytosol]
(Drosophila melanogaster)
Gucy1a1 [cytosol]
(Mus musculus)
Gucy1a1 [cytosol]
(Rattus norvegicus)
Cross References
Guide to Pharmacology - Targets
1288
OpenTargets
ENSG00000164116
ENSEMBL
ENST00000511108
,
ENST00000511507
,
ENSP00000412201
,
ENSP00000421493
,
ENST00000296518
,
ENSP00000426968
,
ENST00000455639
,
ENSP00000426040
,
ENSP00000296518
,
ENSP00000424361
,
ENST00000506455
,
ENST00000513574
ZINC - Substances
GCYA3_HUMAN
ZINC target
Q02108
PRO
Q02108
PDB
7D9U
,
7D9S
,
8HBF
,
3UVJ
,
8HBH
,
7D9R
,
6JT1
,
6JT0
,
7D9T
,
6JT2
,
8HBE
,
4NI2
IntEnz
4.6.1.2
HPA
ENSG00000164116-GUCY1A1
Pharos - Targets
Q02108
Orphanet
GUCY1A1
ZINC - Predictions - Purchasable
GCYA3_HUMAN
HMDB Protein
HMDBP01068
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