Recruitment of FAK to NCAM1:Fyn in lipid rafts

Stable Identifier
R-HSA-391865
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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Recruitment of FAK to NCAM1:Fyn in lipid rafts
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Fyn activation leads to the recruitment and activation of the non-receptor tyrosine kinase FAK. Once recruited to Fyn, FAK undergoes autophosphorylation on tyrosine 397. This tyrosine allows the binding of SH2 domain containing proteins.

Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein tyrosine kinase activity of PTK2 [cytosol]

Physical Entity
PTK2 [cytosol] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Inferred From
Recruitment of FAK to NCAM1:Fyn in lipid rafts (Mus musculus)
Authored
Garapati, P V  (2009-02-24)
Reviewed
Walmod, PS  (2009-05-26)
Maness, PF  (2009-05-26)
Created
Garapati, P V  (2009-02-24)
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