Recruitment of FAK to NCAM1:Fyn in lipid rafts

Stable Identifier
R-HSA-391865
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Fyn activation leads to the recruitment and activation of the non-receptor tyrosine kinase FAK. Once recruited to Fyn, FAK undergoes autophosphorylation on tyrosine 397. This tyrosine allows the binding of SH2 domain containing proteins.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of PTK2 [cytosol]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created