Recruitment of FAK to NCAM1:Fyn in lipid rafts

Stable Identifier
R-HSA-391865
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Fyn activation leads to the recruitment and activation of the non-receptor tyrosine kinase FAK. Once recruited to Fyn, FAK undergoes autophosphorylation on tyrosine 397. This tyrosine allows the binding of SH2 domain containing proteins.

Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of PTK2 [cytosol]

Inferred From
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Created
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