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Spectrin is a protein found at the intracellular surface of the plasma membrane in many cell types. In association with other proteins particularly protein 4.1 and ankyrin it forms hexagonal or pentagonal structures that act as a plasma membrane scaffold for other membrane structures and as an attachment point for cytoskeletal proteins such as actin. The erythrocyte forms of spectrin are the best studied (and not exclusievely expressed in erthrocytes).