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GNRHR2 [plasma membrane]
Stable Identifier
R-HSA-391369
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
GnRH2 receptor, RecName: Full=Putative gonadotropin-releasing hormone II receptor; AltName: Full=Type II GnRH receptor; AltName: Full=GnRH-II-R;
GN Name=GNRHR2;
OS Homo sapiens, GNRR2_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
GNRHRs [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Hormone ligand-binding receptors (Homo sapiens)
GNRHR2 binds GNRH1,2 (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
GNRHR2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96P88 GNRHR2
Gene Names
GNRHR2
Chain
chain:1-292
Reference Genes
HGNC:16341 GNRHR2
UCSC:Q96P88 GNRHR2
Participates
as an input of
GNRHR2 binds GNRH1,2 (Homo sapiens)
as a member of
GNRHRs [plasma membrane] (Homo sapiens)
as a component of
GNRHR2:GNRH1,2 [plasma membrane] (Homo sapiens)
Inferred To
GNRHR2 [plasma membrane]
(Sus scrofa)
gnrhr [plasma membrane]
(Xenopus tropicalis)
gnrhr4 [plasma membrane]
(Danio rerio)
gnrr-1 [plasma membrane]
(Caenorhabditis elegans)
AkhR [plasma membrane]
(Drosophila melanogaster)
GNRHR1/III [plasma membrane]
(Gallus gallus)
Cross References
Guide to Pharmacology - Targets
257
OpenTargets
ENSG00000211451
GeneCards
GNRHR2
PRO
Q96P88
HMDB Protein
HMDBP07714
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