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TAAR1 [plasma membrane]
Stable Identifier
R-HSA-391207
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RecName: Full=Trace amine-associated receptor 1; Short=Trace amine receptor 1; Short=TaR-1;
GN Name=TAAR1; Synonyms=TA1, TAR1, TRAR1;
OS Homo sapiens, TAAR1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Trace amine-associated receptors can bind trace amines (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
TAAR1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96RJ0 TAAR1
Gene Names
TAAR1, TA1, TAR1, TRAR1
Chain
chain:1-339
Reference Genes
BioGPS Gene:134864 TAAR1
COSMIC (genes):TAAR1 TAAR1
CTD Gene:134864 TAAR1
dbSNP Gene:134864 TAAR1
ENSEMBL:ENSG00000146399 TAAR1
HGNC:17734 TAAR1
KEGG:hsa:134864 TAAR1
Monarch:134864 TAAR1
NCBI Gene:134864 TAAR1
OMIM:609333 TAAR1
UCSC:Q96RJ0 TAAR1
Reference Transcript
RefSeq:NM_138327.2 TAAR1
Other Identifiers
11737370_at
134864
17023705
2974577
2974578
2974579
2974580
8129615
ADDON002861.hg
A_23_P93531
GE905225
GO:0001594
GO:0004930
GO:0005886
GO:0007186
GO:0007189
GO:0007193
GO:0007200
GO:0008227
GO:0012505
GO:0016020
GO:0060089
HMNXSV003028315
ILMN_1744056
ILMN_2197164
PH_hs_0018197
TC06002118.hg
Participates
as a member of
Trace amine-associated receptor [plasma membrane] (Homo sapiens)
Inferred To
taar10a [plasma membrane]
(Danio rerio)
npr-42 [plasma membrane]
(Caenorhabditis elegans)
TAAR1 [plasma membrane]
(Bos taurus)
TAAR1 [plasma membrane]
(Mus musculus)
TAAR1 [plasma membrane]
(Rattus norvegicus)
taar1 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_612200.1
ZINC - World Drugs
TAAR1_HUMAN
Guide to Pharmacology - Targets
364
ENSEMBL
ENSP00000275216
,
ENST00000275216
OpenTargets
ENSG00000146399
ZINC - FDA approved
TAAR1_HUMAN
ZINC - Substances
TAAR1_HUMAN
ZINC - Biogenic
TAAR1_HUMAN
ZINC target
Q96RJ0
PRO
Q96RJ0
GlyGen
Q96RJ0
PDB
8W89
,
8W8A
,
8JLN
,
8JLR
,
8JLP
,
8JSO
,
8JLO
,
8W87
,
8JLQ
,
8WC8
,
8UHB
,
8WCA
,
8W88
ZINC - Investigational
TAAR1_HUMAN
ZINC - Metabolites
TAAR1_HUMAN
HPA
ENSG00000146399-TAAR1
Pharos - Targets
Q96RJ0
ZINC - Predictions - Purchasable
TAAR1_HUMAN
HMDB Protein
HMDBP10805
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