Reactome | TAAR9 [plasma membrane]

TAAR9 [plasma membrane]

Stable Identifier

R-HSA-391206

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

RecName: Full=Trace amine-associated receptor 9; AltName: Full=Trace amine receptor 3; Short=TaR-3; GN Name=TAAR9; Synonyms=TA3, TAR3, TRAR3; OS Homo sapiens, TAAR9_HUMAN

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR downstream signalling (Homo sapiens)
    - G alpha (s) signalling events (Homo sapiens)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
      - Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
      - The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
        
        GPCRs that activate Gs [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Amine ligand-binding receptors (Homo sapiens)
        
        Trace amine-associated receptors can bind trace amines (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor:PEA [plasma membrane] (Homo sapiens)
        
        Trace amine-associated receptor [plasma membrane] (Homo sapiens)
        
        TAAR9 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96RI9 TAAR9

Gene Names

TAAR9, TA3, TAR3, TRAR3

Chain

chain:1-348

Reference Genes

BioGPS Gene:134860 TAAR9

COSMIC (genes):TAAR9 TAAR9

CTD Gene:134860 TAAR9

dbSNP Gene:134860 TAAR9

ENSEMBL:ENSG00000237110 TAAR9

HGNC:20977 TAAR9

KEGG:hsa:134860 TAAR9

Monarch:134860 TAAR9

NCBI Gene:134860 TAAR9

OMIM:608282 TAAR9

UCSC:Q96RI9 TAAR9

Reference Transcript

RefSeq:NM_175057.3 TAAR9

Other Identifiers

11743210_at

134860

1553066_PM_at

1553066_at

17012690

2926132

2926133

2926135

2926136

8122127

A_14_P123222

A_23_P168266

GE558726

GO:0001594

GO:0004930

GO:0005515

GO:0005886

GO:0007186

GO:0007189

GO:0016020

GO:0060089

HMNXSV003014627

Hs2Affx.1.7.S1_3p_at

ILMN_1762024

PH_hs_0033331

TC06000992.hg

Participates

as a candidate of

Trace amine-associated receptor [plasma membrane] (Homo sapiens)

Inferred To

taar13e [plasma membrane] (Danio rerio)

taar13c [plasma membrane] (Danio rerio)

TAAR9 [plasma membrane] (Bos taurus)

Taar9 [plasma membrane] (Mus musculus)

Taar9 [plasma membrane] (Rattus norvegicus)

npr-42 [plasma membrane] (Caenorhabditis elegans)

Homologues of TAAR9 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_778227.3

Guide to Pharmacology - Targets

173

ENSEMBL

ENSP00000424607, ENST00000434551

OpenTargets

ENSG00000237110

HPA

ENSG00000237110-TAAR9

PRO

Q96RI9

Pharos - Targets

Q96RI9

GlyGen

Q96RI9