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Heterotrimeric G-protein Gs (inactive) [plasma membrane]
Stable Identifier
R-HSA-391179
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
ADORA2B:Ade-Rib binds heterometric G-protein Gs (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Prostacyclin signalling through prostacyclin receptor (Homo sapiens)
Activated prostacyclin receptor binds G-protein Gs (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Gs activation by prostacyclin receptor (Homo sapiens)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Inactive G alpha (s) reassociates with G beta:gamma (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Participants
components
G alpha (s):GDP [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex [plasma membrane] (Homo sapiens)
Participant Of
output
Inactive G alpha (s) reassociates with G beta:gamma
input
Activated prostacyclin receptor binds G-protein Gs
ADORA2B:Ade-Rib binds heterometric G-protein Gs
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs
hasComponent
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane]
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
Inferred To
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Caenorhabditis elegans)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Canis familiaris)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Danio rerio)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Gallus gallus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Mus musculus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Sus scrofa)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Xenopus tropicalis)
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