p-4Y-SIRPA:CD47 binds SKAP2

Stable Identifier
R-HSA-391157
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
Synonyms
p-Y428,Y452,Y469,Y495-SIRPA:CD47 binds SKAP2, Recruitment of SCAP2 to pSIRP alpha
ReviewStatus
5/5
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p-4Y-SIRPA:CD47 binds SKAP2
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SRC-family-associated phosphoprotein 2 (SCAP2) has been shown to bind to SIRP alpha. Evidence from immunoprecipitation experiments performed in COS-7 lysates suggests that the SH3 domain of SCAP2 is involved in the interaction.
Literature References
PubMed ID Title Journal Year
10469599 SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages

Timms, JF, Raab, M, Neel, BG, Marie-Cardine, A, Swanson, KD, Schraven, B, Rudd, CE

Curr Biol 1999
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Orthologous Events
p-4Y-SIRPA:CD47 binds SKAP2 (Bos taurus)
p-4Y-SIRPA:CD47 binds SKAP2 (Canis familiaris)
p-4Y-SIRPA:CD47 binds SKAP2 (Gallus gallus)
p-4Y-SIRPA:CD47 binds SKAP2 (Mus musculus)
p-4Y-SIRPA:CD47 binds SKAP2 (Rattus norvegicus)
p-4Y-SIRPA:CD47 binds SKAP2 (Sus scrofa)
Authored
Garapati, P V  (2009-02-12)
Reviewed
Barclay, AN  (2010-05-20)
Created
Garapati, P V  (2009-02-12)
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