p-4Y-SIRPA:CD47 binds GRB2-1

Stable Identifier
R-HSA-391153
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
Recruitment of Grb2 to pSIRP alpha
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GRB2 binds to phosphorylated tyrosine residues in SIRP alpha (SIRPA) in vitro; this interaction has negative regulatory effects on cellular responses induced by growth factors, oncogenes or insulin.

Literature References
PubMed ID Title Journal Year
9062191 A family of proteins that inhibit signalling through tyrosine kinase receptors

Kharitonenkov, A, Chen, Z, Sures, I, Wang, H, Schilling, J, Ullrich, A

Nature 1997
Participants
Participant Of
Orthologous Events
Authored
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Created
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