p-4Y-SIRPA:CD47 binds PTK2B

Stable Identifier
R-HSA-391152
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
Synonyms
Recruitment of PYK2 to pSIRP alpha
ReviewStatus
5/5
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p-4Y-SIRPA:CD47 binds PTK2B
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Protein-tyrosine kinase 2-beta (PTK2B, PYK2, FADK2), a cytosolic tyrosine kinase related to FAK, has been shown to complex with SIRP alpha.
Literature References
PubMed ID Title Journal Year
10469599 SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages

Timms, JF, Swanson, KD, Marie-Cardine, A, Raab, M, Rudd, CE, Schraven, B, Neel, BG

Curr Biol 1999
12023008 SHPS-1, a multifunctional transmembrane glycoprotein

Oshima, K, Ruhul Amin, AR, Suzuki, A, Hamaguchi, M, Matsuda, S

FEBS Lett 2002
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Orthologous Events
p-4Y-SIRPA:CD47 binds PTK2B (Bos taurus)
p-4Y-SIRPA:CD47 binds PTK2B (Canis familiaris)
p-4Y-SIRPA:CD47 binds PTK2B (Gallus gallus)
p-4Y-SIRPA:CD47 binds PTK2B (Mus musculus)
p-4Y-SIRPA:CD47 binds PTK2B (Rattus norvegicus)
p-4Y-SIRPA:CD47 binds PTK2B (Sus scrofa)
Authored
Garapati, P V  (2009-02-12)
Reviewed
Barclay, AN  (2010-05-20)
Created
Garapati, P V  (2009-02-12)
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