p-4Y-SIRPA:CD47:SKAP2 binds FYB

Stable Identifier
R-HSA-391151
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
Synonyms
Recruitment of FYB to pSIRP alpha
ReviewStatus
5/5
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p-4Y-SIRPA:CD47:SKAP2 binds FYB
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The Fyn binding protein FYB (SLAP130, ADAP) has been found to associate with SIRP alpha (SIRPA). Recruitment of FYB to SIRPA requires SKAP2.
Literature References
PubMed ID Title Journal Year
10469599 SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages

Timms, JF, Raab, M, Neel, BG, Marie-Cardine, A, Swanson, KD, Schraven, B, Rudd, CE

Curr Biol 1999
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Orthologous Events
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Bos taurus)
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Canis familiaris)
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Gallus gallus)
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Mus musculus)
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Rattus norvegicus)
p-4Y-SIRPA:CD47:SKAP2 binds FYB (Sus scrofa)
Authored
Garapati, P V  (2009-02-12)
Reviewed
Barclay, AN  (2010-05-20)
Created
Garapati, P V  (2009-02-12)
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