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HTR7 [plasma membrane]
Stable Identifier
R-HSA-391010
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
5-HT7 receptor, RecName: Full=5-hydroxytryptamine receptor 7; Short=5-HT-7; Short=5HT7; AltName: Full=5-HT-X; AltName: Full=Serotonin receptor 7;
GN Name=HTR7;
OS Homo sapiens, 5HT7R_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Serotonin receptors (Homo sapiens)
5-HT4, 6 and 7 receptors can bind serotonin (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
HTR4,6,7 [plasma membrane] (Homo sapiens)
HTR7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P34969 HTR7
Gene Names
HTR7
Chain
chain:1-479
Reference Genes
BioGPS Gene:3363 HTR7
COSMIC (genes):HTR7 HTR7
CTD Gene:3363 HTR7
dbSNP Gene:3363 HTR7
ENSEMBL:ENSG00000148680 HTR7
HGNC:5302 HTR7
KEGG:hsa:3363 HTR7
Monarch:3363 HTR7
NCBI Gene:3363 HTR7
OMIM:182137 HTR7
UCSC:P34969 HTR7
Reference Transcript
RefSeq:NM_019859.4 HTR7
RefSeq:NM_019860.4 HTR7
RefSeq:NM_000872.5 HTR7
Participates
as a member of
HTR4,6,7 [plasma membrane] (Homo sapiens)
Inferred To
5-HT7 [plasma membrane]
(Drosophila melanogaster)
HTR7 [plasma membrane]
(Bos taurus)
HTR7 [plasma membrane]
(Canis familiaris)
HTR7 [plasma membrane]
(Gallus gallus)
HTR7 [plasma membrane]
(Sus scrofa)
ser-7 [plasma membrane]
(Caenorhabditis elegans)
htr7a [plasma membrane]
(Danio rerio)
Htr7 [plasma membrane]
(Mus musculus)
Htr7 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_000863.1
,
NP_062873.1
,
NP_062874.1
ZINC - World Drugs
5HT7R_HUMAN
Guide to Pharmacology - Targets
12
ENSEMBL
ENSP00000337949
,
ENSP00000277874
,
ENSG00000148680
,
ENST00000336152
,
ENST00000277874
,
ENSP00000360784
,
ENST00000371719
OpenTargets
ENSG00000148680
ZINC - FDA approved
5HT7R_HUMAN
ZINC - Substances
5HT7R_HUMAN
ZINC - Biogenic
5HT7R_HUMAN
ZINC target
P34969
PRO
P34969
GlyGen
P34969
PDB
7XTC
ZINC - Investigational
5HT7R_HUMAN
ZINC - Metabolites
5HT7R_HUMAN
GeneCards
HTR7
HPA
ENSG00000148680-HTR7
Pharos - Targets
P34969
ZINC - Predictions - Purchasable
5HT7R_HUMAN
HMDB Protein
HMDBP02268
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