Reactome | HTR4,6,7 [plasma membrane]

HTR4,6,7 [plasma membrane]

Stable Identifier

R-HSA-390942

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

5-HT4/6/7 receptor

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Leishmania infection (Homo sapiens)
    - Leishmania parasite growth and survival (Homo sapiens)
      - Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
        
        ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        HTR4,6,7:5HT [plasma membrane] (Homo sapiens)
        
        HTR4,6,7 [plasma membrane] (Homo sapiens)

Participants

members

Participant Of

input

5-HT4, 6 and 7 receptors can bind serotonin

hasMember

GPCRs that activate Gs [plasma membrane]

hasComponent

HTR4,6,7:5HT [plasma membrane]

Inferred To

HTR4,6,7 [plasma membrane] (Bos taurus)

HTR4,6,7 [plasma membrane] (Caenorhabditis elegans)

HTR4,6,7 [plasma membrane] (Canis familiaris)

HTR4,6,7 [plasma membrane] (Danio rerio)

HTR4,6,7 [plasma membrane] (Drosophila melanogaster)

HTR4,6,7 [plasma membrane] (Gallus gallus)

HTR4,6,7 [plasma membrane] (Mus musculus)

HTR4,6,7 [plasma membrane] (Rattus norvegicus)

HTR4,6,7 [plasma membrane] (Sus scrofa)

HTR4,6,7 [plasma membrane] (Xenopus tropicalis)

© 2021 Reactome

Cite Us!