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HRH3 [plasma membrane]
Stable Identifier
R-HSA-390866
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Histamine H3 receptor, RecName: Full=Histamine H3 receptor; Short=HH3R; AltName: Full=G-protein coupled receptor 97;
GN Name=HRH3; Synonyms=GPCR97;
OS Homo sapiens, HRH3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
Histamine receptors (Homo sapiens)
HRH3 binds Hist (Homo sapiens)
HRH3 [plasma membrane] (Homo sapiens)
HRH3:Hist [plasma membrane] (Homo sapiens)
HRH3 [plasma membrane] (Homo sapiens)
HRH3 binds pitosilant (Homo sapiens)
HRH3 [plasma membrane] (Homo sapiens)
HRH3:pitosilant [plasma membrane] (Homo sapiens)
HRH3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y5N1 HRH3
Gene Names
HRH3, GPCR97
Chain
chain:1-445
Reference Genes
BioGPS Gene:11255 HRH3
COSMIC (genes):HRH3 HRH3
CTD Gene:11255 HRH3
dbSNP Gene:11255 HRH3
ENSEMBL:ENSG00000101180 HRH3
ENSEMBL:ENSG00000101180.17 HRH3
HGNC:5184 HRH3
KEGG Gene (Homo sapiens):11255 HRH3
Monarch:11255 HRH3
NCBI Gene:11255 HRH3
OMIM:604525 HRH3
UCSC:Q9Y5N1 HRH3
Reference Transcript
RefSeq:NM_007232.2 HRH3
RefSeq:XM_005260266.3 HRH3
Other Identifiers
11255
11735334_a_at
11746741_a_at
11751743_a_at
11753585_a_at
1555215_PM_a_at
1555215_a_at
1555715_PM_a_at
1555715_a_at
16920923
220447_3p_at
220447_PM_at
220447_at
221663_3p_x_at
221663_PM_x_at
221663_x_at
3912937
3912938
3912939
3912940
3912941
3912942
3912943
3912944
3912945
3912946
3912947
3912950
3912951
3912952
3912953
3912954
8067394
86263_r_at
A_24_P301837
GE62968
GO:0001505
GO:0004930
GO:0004969
GO:0004993
GO:0005886
GO:0007165
GO:0007186
GO:0007187
GO:0007197
GO:0007268
GO:0007269
GO:0014050
GO:0014061
GO:0014063
GO:0016020
GO:0016907
GO:0023052
GO:0030425
GO:0045202
GO:0050877
GO:0050890
GO:0060089
GO:0098664
GO:0098793
HMNXSV003050029
Hs2.251399.4.S1_3p_s_at
ILMN_1694273
PH_hs_0013303
TC20001006.hg
g12248409_3p_a_at
g12248409_3p_s_at
g12248409_3p_x_at
g6005781_3p_a_at
g6005781_3p_s_at
Participates
as a component of
HRH3:Hist [plasma membrane] (Homo sapiens)
HRH3:pitosilant [plasma membrane] (Homo sapiens)
as an input of
HRH3 binds Hist (Homo sapiens)
HRH3 binds pitosilant (Homo sapiens)
Inferred To
LOC116411746 [plasma membrane]
(Xenopus tropicalis)
gar-2 [plasma membrane]
(Caenorhabditis elegans)
HRH3 [plasma membrane]
(Bos taurus)
HRH3 [plasma membrane]
(Canis familiaris)
HRH3 [plasma membrane]
(Gallus gallus)
HRH3 [plasma membrane]
(Sus scrofa)
HRH3 [plasma membrane]
(Xenopus tropicalis)
Hrh3 [plasma membrane]
(Mus musculus)
Hrh3 [plasma membrane]
(Rattus norvegicus)
gar-3 [plasma membrane]
(Caenorhabditis elegans)
Homologues of HRH3 [plasma membrane]
(Caenorhabditis elegans)
Homologues of HRH3 [plasma membrane]
(Drosophila melanogaster)
Homologues of HRH3 [plasma membrane]
(Xenopus tropicalis)
mAChR-B [plasma membrane]
(Drosophila melanogaster)
mAChR-A [plasma membrane]
(Drosophila melanogaster)
LOC100334962 [plasma membrane]
(Danio rerio)
gar-1 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_009163.2
,
XP_005260323.1
ZINC - World Drugs
HRH3_HUMAN
Guide to Pharmacology - Targets
264
OpenTargets
ENSG00000101180
ZINC - FDA approved
HRH3_HUMAN
ZINC - Substances
HRH3_HUMAN
ZINC - Biogenic
HRH3_HUMAN
ZINC target
Q9Y5N1
PRO
Q9Y5N1
PDB
7F61
ZINC - Investigational
HRH3_HUMAN
ZINC - Metabolites
HRH3_HUMAN
GeneCards
Q9Y5N1
HPA
ENSG00000101180-HRH3
Ensembl
ENST00000340177
,
ENSG00000101180
,
ENSP00000342560
Pharos - Targets
Q9Y5N1
ZINC - Predictions - Purchasable
HRH3_HUMAN
HMDB Protein
HMDBP02715
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