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Exchange of ADP for ATP in CCT/TriC:actin complex
Stable Identifier
R-HSA-390459
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding (Homo sapiens)
Folding of actin by CCT/TriC (Homo sapiens)
Exchange of ADP for ATP in CCT/TriC:actin complex (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The interaction between CCT and unfolded target proteins is thought to occur when CCT is in its ADP-bound state. ADP is then exchanged for ATP in CCT.
Participants
Input
x 8
ATP [cytosol]
CCT/TRiC:ADP:actin [cytosol]
(Homo sapiens)
Output
x 8
ADP [cytosol]
CCT/TRiC:ATP:actin [cytosol]
(Homo sapiens)
Participates
as an event of
Folding of actin by CCT/TriC (Homo sapiens)
Inferred From
Exchange of ADP for ATP in CCT/TriC:actin complex (Bos taurus)
Authored
Matthews, L (2008-12-01)
Reviewed
Cowan, NJ (2009-01-21)
Created
Matthews, L (2009-02-09)
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