Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA

Stable Identifier
R-HSA-390302
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
peroxisomal matrix
Synonyms
tetracosenoyl-CoA + 8 O2 + 8 H2O + 8 NAD+ + 8 CoASH => octanoyl-CoA + 8 H2O2 + 8 NADH + 8 H+ + 8 acetyl-CoA
ReviewStatus
5/5
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Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA
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In eight cycles of beta-oxidation mediated by the same enzyme activities responsible for the conversion of hexacosanoyl-CoA to tetracosenoyl-CoA, the latter molecule is converted to octanoyl-CoA. Eight molecules each of O2, H2O, NAD+, and CoASH are consumed in the process and eight molecules of H2O2 and NADH + H+ are generated, together with eight molecules of acetyl-CoA (Wanders and Waterham 2006).
Literature References
PubMed ID Title Journal Year
16756494 Biochemistry of mammalian peroxisomes revisited

Wanders, RJA, Waterham, HR

Annu Rev Biochem 2006
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Output
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Event Information
Go Biological Process
fatty acid beta-oxidation (0006635)
Authored
D'Eustachio, P  (2009-03-16)
Reviewed
Jassal, B  (2009-02-27)
Created
D'Eustachio, P  (2009-01-25)
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