Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding

Stable Identifier
R-HSA-389958
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
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In the case of actin and tubulin folding, and perhaps other substrates, the emerging polypeptide chain is transferred from the ribosome to TRiC via Prefoldin (Vainberg et al., 1998).
Literature References
PubMed ID Title Journal Year
9630229 Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin

Klein, HL, Rommelaere, H, Vandekerckhove, J, Lewis, SA, Cowan, NJ, Ampe, C, Vainberg, IE

Cell 1998
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Authored
Matthews, L  (2008-12-01)
Reviewed
Cowan, NJ  (2009-01-21)
Created
Matthews, L  (2009-01-22)
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