PXLP-AGXT [peroxisomal matrix]

Stable Identifier
R-HSA-389669
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal matrix
Synonyms
Alanine-glyoxylate aminotransferase, Serine-pyruvate aminotransferase, AGXT
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
12899834 Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1

Roe, SM, Bartlam, M, Pearl, LH, Danpure, CJ, Rao, Z, Zhang, X, Hou, Y

J Mol Biol 2003
External Reference Information
External Reference
UniProt:P21549 AGXT
Gene Names
AGXT, AGT1, SPAT
Chain
chain:1-392
Reference Genes
BioGPS Gene:189 AGXT
COSMIC (genes):AGXT AGXT
CTD Gene:189 AGXT
dbSNP Gene:189 AGXT
ENSEMBL:ENSG00000172482 AGXT
HGNC:341 AGXT
KEGG:hsa:189 AGXT
Monarch:189 AGXT
NCBI Gene:189 AGXT
OMIM:604285 AGXT
UCSC:P21549 AGXT
Reference Transcript
Other Identifiers
11731623_s_at
11761132_at
11762478_at
16893287
189
206957_PM_at
206957_at
210326_PM_at
210326_at
210327_PM_s_at
210327_s_at
2535977
2535978
2535979
2535981
2535983
2535984
2535985
2535986
2535987
2535988
2535989
2535990
2535991
2535992
2535993
2535994
2535995
2535996
2535997
2535998
2535999
37880_at
8049737
A_23_P83590
A_33_P3250278
GE502660
GE59784
GO:0003824
GO:0004760
GO:0005515
GO:0005777
GO:0005782
GO:0005829
GO:0006520
GO:0006563
GO:0006790
GO:0007219
GO:0008453
GO:0008483
GO:0009436
GO:0016597
GO:0016740
GO:0019265
GO:0019448
GO:0030170
GO:0042802
GO:0042803
GO:0042853
GO:0043226
GO:0043231
GO:0046487
GO:0046724
HMNXSV003011348
ILMN_1709796
PH_hs_0008554
TC02001471.hg
X53414_at
g219432_3p_s_at
g7706736_3p_at
Participates
as a member of
as a component of
Other forms of this molecule
AGXT [cytosol]
Inferred To
AGXT [peroxisomal matrix] (Canis familiaris)
PXLP-AGXT [peroxisomal matrix] (Bos taurus)
PXLP-AGXT [peroxisomal matrix] (Caenorhabditis elegans)
PXLP-AGXT [peroxisomal matrix] (Danio rerio)
PXLP-AGXT [peroxisomal matrix] (Dictyostelium discoideum)
PXLP-AGXT [peroxisomal matrix] (Drosophila melanogaster)
PXLP-AGXT [peroxisomal matrix] (Gallus gallus)
PXLP-AGXT [peroxisomal matrix] (Mus musculus)
PXLP-AGXT [peroxisomal matrix] (Rattus norvegicus)
PXLP-AGXT [peroxisomal matrix] (Sus scrofa)
PXLP-AGXT [peroxisomal matrix] (Xenopus tropicalis)
Modified Residues
Name
N6-pyridoxal phosphate-L-lysine at 209
Coordinate
209
PsiMod Name
N6-pyridoxal phosphate-L-lysine [MOD:00128]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-pyridoxal phosphate-L-lysine.
Cross References
ENSEMBL
OpenTargets
IntEnz
HPA
PRO
Pharos - Targets
Orphanet
HMDB Protein
PDB
Interactors (4)
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