Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
HACL1 [peroxisomal matrix]
Stable Identifier
R-HSA-389600
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal matrix
Synonyms
2-hydroxyacyl-CoA lyase 1, 2-hydroxyphytanoyl-CoA lyase
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Peroxisomal lipid metabolism (Homo sapiens)
Alpha-oxidation of phytanate (Homo sapiens)
2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Homo sapiens)
HACL1 tetramer [peroxisomal matrix] (Homo sapiens)
HACL1 holoenzyme monomer [peroxisomal matrix] (Homo sapiens)
HACL1 [peroxisomal matrix] (Homo sapiens)
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
HACL1 [peroxisomal matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UJ83 HACL1
Gene Names
HACL1, HPCL, HPCL2, PHYH2, HSPC279
Chain
chain:1-578
Reference Genes
BioGPS Gene:26061 HACL1
COSMIC (genes):HACL1 HACL1
CTD Gene:26061 HACL1
dbSNP Gene:26061 HACL1
ENSEMBL:ENSG00000131373 HACL1
ENSEMBL_homo_sapiens_GENE:ENSG00000131373.15 HACL1
HGNC:17856 HACL1
KEGG Gene (Homo sapiens):26061 HACL1
Monarch:26061 HACL1
NCBI Gene:26061 HACL1
OMIM:604300 HACL1
UCSC:Q9UJ83 HACL1
Reference Transcript
RefSeq:NM_001284413.1 HACL1
RefSeq:NM_012260.3 HACL1
RefSeq:NM_001284416.1 HACL1
RefSeq:NM_001284415.1 HACL1
Other Identifiers
11754723_a_at
16951220
223211_PM_at
223211_at
26061
2664405
2664406
2664411
2664412
2664414
2664416
2664420
2664421
2664423
2664424
2664425
2664429
2664430
2664431
2664433
2664434
2664435
2664436
2664437
2664438
2664439
2664440
2664442
2664443
53979_at
8085608
A_23_P121182
GE58477
GO:0000287
GO:0001561
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005777
GO:0005782
GO:0005829
GO:0006625
GO:0006629
GO:0006631
GO:0006886
GO:0007031
GO:0016829
GO:0016830
GO:0030976
GO:0042802
GO:0043226
GO:0043231
GO:0046872
GO:0097089
GO:0106359
GO:0106376
GO:1903512
HMNXSV003037865
ILMN_1723414
PH_hs_0003973
TC03003336.hg
g12804440_3p_at
Participates
as a member of
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
as a component of
HACL1 holoenzyme monomer [peroxisomal matrix] (Homo sapiens)
Other forms of this molecule
HACL1 [cytosol]
Inferred To
hacl1 [peroxisomal matrix]
(Danio rerio)
hacl1 [peroxisomal matrix]
(Xenopus tropicalis)
Hacl [peroxisomal matrix]
(Drosophila melanogaster)
hacl-1 [peroxisomal matrix]
(Caenorhabditis elegans)
HACL1 [peroxisomal matrix]
(Bos taurus)
HACL1 [peroxisomal matrix]
(Dictyostelium discoideum)
HACL1 [peroxisomal matrix]
(Gallus gallus)
HACL1 [peroxisomal matrix]
(Mus musculus)
HACL1 [peroxisomal matrix]
(Rattus norvegicus)
HACL1 [peroxisomal matrix]
(Saccharomyces cerevisiae)
HACL1 [peroxisomal matrix]
(Schizosaccharomyces pombe)
HACL1 [peroxisomal matrix]
(Sus scrofa)
LOC608697 [peroxisomal matrix]
(Canis familiaris)
Cross References
RefSeq
NP_001271344.1
,
NP_001271342.1
,
NP_001271345.1
,
NP_036392.2
OpenTargets
ENSG00000131373
GeneCards
Q9UJ83
HPA
ENSG00000131373-HACL1
Ensembl
ENST00000456194
,
ENSP00000390699
,
ENSP00000403656
,
ENST00000457447
,
ENST00000321169
,
ENSP00000404883
,
ENSG00000131373
,
ENSP00000323811
,
ENST00000451445
PRO
Q9UJ83
Pharos - Targets
Q9UJ83
HMDB Protein
HMDBP08729
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text