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HCRTR2:HCRT(70-97) [plasma membrane]
Stable Identifier
R-HSA-389449
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Orexin 2 receptor:Orexin B
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
HCRTR2:HCRT(70-97) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
HCRTR2:HCRT(70-97) [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
HCRTR2:HCRT(70-97) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
HCRTR2:HCRT(70-97) [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
HCRTR2:HCRT(70-97) [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Orexin and neuropeptides FF and QRFP bind to their respective receptors (Homo sapiens)
Orexin 2 receptor can bind orexin-B neuropeptide (Homo sapiens)
HCRTR2:HCRT(70-97) [plasma membrane] (Homo sapiens)
Participants
components
HCRT(70-97) [extracellular region] (Homo sapiens)
HCRTR2 [plasma membrane] (Homo sapiens)
Participant Of
output
Orexin 2 receptor can bind orexin-B neuropeptide
hasMember
Ligand:GPCR complexes that activate Gq/11 [plasma membrane]
Inferred To
HCRTR2:HCRT(70-97) [plasma membrane] (Canis familiaris)
HCRTR2:HCRT(70-97) [plasma membrane] (Danio rerio)
HCRTR2:HCRT(70-97) [plasma membrane] (Gallus gallus)
HCRTR2:HCRT(70-97) [plasma membrane] (Mus musculus)
HCRTR2:HCRT(70-97) [plasma membrane] (Rattus norvegicus)
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