The orphan QRFP receptor can bind neuropeptide QRFP

Stable Identifier
Reaction [binding]
Homo sapiens
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The orphan QRFP receptor (SP9155) (Lee DK et al, 2001) shares a high sequence homology with the neuropeptide FF receptor. It mediates the activity of neuropeptide QRFP (Jiang Y et al, 2003), which is suspected to have orexigenic activity, via the G alpha-q/11 subunit (Langmead CJ et al, 2000).
Literature References
PubMed ID Title Journal Year
11030716 Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor

Herdon, HJ, Hirst, WD, Price, GW, Szekeres, PG, Ratcliffe, SJ, Jones, DN, Chambers, JK, Langmead, CJ

Br J Pharmacol 2000
12714592 Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155

Gustafson, EL, Greene, J, Qiu, P, Yadav, D, Jiang, Y, Murgolo, N, Zhang, FL, Behan, J, Bayne, M, Monsma F, Jr, Zeng, M, Laz, TM, Wang, L, Vassileva, G, Luo, L, Wang, S, Laverty, M

J Biol Chem 2003
11574155 Discovery and mapping of ten novel G protein-coupled receptor genes

Evans, JF, Nguyen, T, George, SR, O'Dowd, BF, Lewis, T, Arkhitko, O, Lee, DK, Cheng, R, Lynch, KR, Vanti, WB

Gene 2001
Orthologous Events
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