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CSF1 dimer [extracellular region]
Stable Identifier
R-HSA-389151
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Synonyms
M-CSF dimer
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
CSF1 dimer binds CSF1R or IL34 (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:CSF1R [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer binds SRC family kinases FYN,HCK,SRC,YES1 (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds CBL (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:CBL [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK binds GRB2:SOS1 (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:GRB2:SOS1 [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1 (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:GRB2:SOS1 [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1R dimerizes (Homo sapiens)
CSF1 dimer,IL34 dimer:CSF1R [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1R trans-autophosphorylates on multiple tyrosine and serine residues (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb-p-Y561-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb-p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1R trans-autophosphorylates on tyrosine-561 (Homo sapiens)
CSF1 dimer,IL34 dimer:CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1R-associated SOS1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:GRB2:SOS1 [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:p-Y-CBL:GRB2:SOS1:p-Y-GAB2:p-Y-GAB3:GRAP2:INPP5D:INPPL1:PI3K:PTPN11:p-Y-SHC1:p-Y-PLCG2 [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb,p-8Y-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:CBL [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
p-Y-CBL autoubiquitinates and multiubiquitinates p-Y561-CSF1R in CSF1 dimer:p-Y561-CSF1R dimer:p-Y-CBL (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb-p-Y561-CSF1R dimer:SFK:PolyUb,p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:PolyUb-p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK:p-Y-CBL [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer:SFK [plasma membrane] (Homo sapiens)
CSF1 dimer,IL34 dimer:p-Y561-CSF1R dimer [plasma membrane] (Homo sapiens)
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
CSF1 dimer [extracellular region] (Homo sapiens)
Participants
components
x 2
CSF1 [extracellular region]
(Homo sapiens)
Participates
as a member of
CSF1 dimer, IL34 dimer [extracellular region] (Homo sapiens)
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