Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
NPY1R [plasma membrane]
Stable Identifier
R-HSA-388896
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
RecName: Full=Neuropeptide Y receptor type 1; AltName: Full=NPY1-R;
GN Name=NPY1R; Synonyms=NPYR, NPYY1;
OS Homo sapiens, NPY1R_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors:NPY receptor ligands [plasma membrane] (Homo sapiens)
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
NPY1R [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P25929 NPY1R
Gene Names
NPY1R, NPYR, NPYY1
Chain
chain:1-384
Reference Genes
BioGPS Gene:4886 NPY1R
COSMIC (genes):NPY1R NPY1R
CTD Gene:4886 NPY1R
dbSNP Gene:4886 NPY1R
ENSEMBL:ENSG00000164128 NPY1R
ENSEMBL_homo_sapiens_GENE:ENSG00000164128.7 NPY1R
HGNC:7956 NPY1R
KEGG Gene (Homo sapiens):4886 NPY1R
Monarch:4886 NPY1R
NCBI Gene:4886 NPY1R
OMIM:162641 NPY1R
UCSC:P25929 NPY1R
Reference Transcript
RefSeq:NM_000909.5 NPY1R
RefSeq:XM_011532010.2 NPY1R
RefSeq:XM_005263031.3 NPY1R
Other Identifiers
11727386_a_at
11727387_s_at
11751576_a_at
16981099
205440_PM_s_at
205440_s_at
2792128
2792129
2792130
2792132
2792133
2792134
2792138
2792139
35437_at
4886
8103494
90580_at
GE58241
GO:0001601
GO:0001602
GO:0003013
GO:0003151
GO:0004930
GO:0004983
GO:0005515
GO:0005886
GO:0005975
GO:0006006
GO:0007165
GO:0007186
GO:0007187
GO:0007193
GO:0007218
GO:0007626
GO:0007631
GO:0008188
GO:0008217
GO:0016020
GO:0019233
GO:0023052
GO:0040014
GO:0042923
GO:0043005
GO:0048856
GO:0050877
GO:0060089
HMNXSV003016082
ILMN_1667947
L07615_at
M88461_s_at
PH_hs_0030764
TC04001698.hg
g4505444_3p_s_at
Participates
as a member of
Neuropeptide Y receptors [plasma membrane] (Homo sapiens)
Inferred To
npy1r [plasma membrane]
(Xenopus tropicalis)
Npy1r [plasma membrane]
(Danio rerio)
Npy1r [plasma membrane]
(Mus musculus)
Npy1r [plasma membrane]
(Rattus norvegicus)
NPY1R [plasma membrane]
(Bos taurus)
NPY1R [plasma membrane]
(Canis familiaris)
NPY1R [plasma membrane]
(Gallus gallus)
Cross References
RefSeq
XP_005263088.1
,
XP_011530312.1
,
NP_000900.1
Guide to Pharmacology - Targets
305
OpenTargets
ENSG00000164128
ZINC - Substances
NPY1R_HUMAN
ZINC target
P25929
PRO
P25929
PDB
5ZBQ
,
7X9A
,
7VGX
ZINC - Investigational
NPY1R_HUMAN
GeneCards
P25929
HPA
ENSG00000164128-NPY1R
Ensembl
ENST00000296533
,
ENSP00000354652
,
ENSG00000164128
Pharos - Targets
P25929
ZINC - Predictions - Purchasable
NPY1R_HUMAN
HMDB Protein
HMDBP13635
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text