Reactome | MSH [extracellular region]

MSH [extracellular region]

Stable Identifier

R-HSA-388597

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Melanocyte stimulating hormone

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Leishmania infection (Homo sapiens)
    - Leishmania parasite growth and survival (Homo sapiens)
      - Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
        
        ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
        
        ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
        
        MSH:Melanocortin receptors [plasma membrane] (Homo sapiens)
        
        MSH [extracellular region] (Homo sapiens)

Participants

members

Participant Of

input

Melanocortin receptors bind melanocortins

hasMember

Ligands of GPCRs that activate Gs [extracellular region]

hasComponent

MSH:Melanocortin receptors [plasma membrane]

Inferred To

Pomc [extracellular region] (Mus musculus)

Pomc [extracellular region] (Rattus norvegicus)

pomca [extracellular region] (Danio rerio)

pomc [extracellular region] (Xenopus tropicalis)

MSH [extracellular region] (Sus scrofa)

POMC [extracellular region] (Bos taurus)

POMC [extracellular region] (Canis familiaris)

POMC [extracellular region] (Gallus gallus)

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