Grb7 an adapter protein contains a single SH2 domain, a pleckstrin homology (PH) domain, and a proline-rich region. Similar to Grb2, Grb7 interacts with phosphorylated tyrosines in pYXNX motifs, including Tyr716 and Tyr775 of the PDGF beta-receptor.
Heldin, CH, Ostman, A, Rönnstrand, L
Heldin, CH, Westermark, B
Yokote, K, Margolis, B, Heldin, CH, Claesson-Welsh, L
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