Reactome | PDGFC-1 [endoplasmic reticulum lumen]

PDGFC-1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-381912

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Platelet-derived growth factor C precursor isoform 1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NRA1-1 PDGFC

Gene Names

PDGFC, SCDGF, UNQ174/PRO200

Other Identifiers

0004010050

11723337_a_at

11723338_a_at

11751373_a_at

16980946

218718_at

222719_s_at

2791196

2791198

2791199

2791200

2791201

2791202

2791205

2791206

2791207

2791208

2791222

2791229

2791246

2791247

2791248

2791249

2791250

2791251

45217_at

56034

61027_r_at

61792_at

8103399

A_23_P58396

A_24_P163168

GE62448

GO:0000139

GO:0003674

GO:0005161

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005783

GO:0005788

GO:0005794

GO:0005829

GO:0005886

GO:0006464

GO:0007165

GO:0007171

GO:0007275

GO:0007417

GO:0008083

GO:0008150

GO:0008283

GO:0008284

GO:0009790

GO:0009887

GO:0009986

GO:0014068

GO:0016020

GO:0022607

GO:0030335

GO:0031954

GO:0040011

GO:0042592

GO:0042803

GO:0043226

GO:0043406

GO:0048008

GO:0048146

GO:0048565

GO:0048568

GO:0048856

GO:0048870

GO:0050730

GO:0051301

GO:0051781

GO:0060348

GO:0065003

GO:0070062

GO:0070374

GO:0070851

GO:0071230

GO:0120162

ILMN_1683023

PH_hs_0003147

TC04001673.hg

TC04002799.hg

g9392293_3p_a_at

g9994186_3p_at

Participant Of

hasComponent

PDGF-C chain precursor dimer [endoplasmic reticulum lumen]

Other forms of this molecule

PDGFC-1(24-234) [extracellular region]

PDGFC-1(235-345) [extracellular region]

PDGFC-1(23-345) [extracellular region]

PDGFC-1 [Golgi membrane]

Inferred To

PDGFC [endoplasmic reticulum lumen] (Bos taurus)

PDGFC [endoplasmic reticulum lumen] (Canis familiaris)

PDGFC [endoplasmic reticulum lumen] (Gallus gallus)

PDGFC [endoplasmic reticulum lumen] (Sus scrofa)

pdgfc [endoplasmic reticulum lumen] (Danio rerio)

radx [endoplasmic reticulum lumen] (Xenopus tropicalis)

pvf-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)

Homologues of PDGFC-1 [endoplasmic reticulum lumen] (Danio rerio)

Pvf1 [endoplasmic reticulum lumen] (Drosophila melanogaster)

Pdgfc [endoplasmic reticulum lumen] (Mus musculus)

Pdgfc [endoplasmic reticulum lumen] (Rattus norvegicus)

Cross References

RefSeq

XP_016863945.1, NP_057289.1

OpenTargets

ENSG00000145431

GeneCards

Q9NRA1

HPA

ENSG00000145431-PDGFC

Ensembl

ENST00000422544, ENSP00000410048, ENST00000502773, ENSP00000422464, ENSG00000145431

PRO

Q9NRA1

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P16234 PDGFRA	47	PDGFRA N659K [plasma membrane] (R-HSA-9671535) PDGFRA L629P [plasma membrane] (R-HSA-9673596) PDGFRA T674I [plasma membrane] (R-HSA-9673603) PDGFRA S601P [plasma membrane] (R-HSA-9673600) PDGFRA Y288C [endoplasmic reticulum membrane] (R-HSA-9671971) PDGFRA del375-455 [endoplasmic reticulum membrane] (R-HSA-9673609) p-11Y PDGFRA Y288C [endoplasmic reticulum membrane] (R-HSA-9672027) p-11Y PDGFRA del375-455 [endoplasmic reticulum membrane] (R-HSA-9673634) PDGFRA D842_M844del [plasma membrane] (R-HSA-9671526) PDGFRA D842Y [plasma membrane] (R-HSA-9671956) PDGFRA D842V [plasma membrane] (R-HSA-9671549) PDGFRA D843_846del [plasma membrane] (R-HSA-9671537) PDGFRA D842_H845del [plasma membrane] (R-HSA-9671545) PDGFRA D842del [plasma membrane] (R-HSA-9671538) PDGFRA D842_I843delinsV [plasma membrane] (R-HSA-9671563) PDGFRA D846Y [plasma membrane] (R-HSA-9671958) PDGFRA D843_845del [plasma membrane] (R-HSA-9671552) PDGFRA D842_D846del [plasma membrane] (R-HSA-9671547) PDGFRA N848K [plasma membrane] (R-HSA-9671961) PDGFRA Y849C [plasma membrane] (R-HSA-9671974) PDGFRA D843_844del [plasma membrane] (R-HSA-9671559) PDGFRA D846V [plasma membrane] (R-HSA-9674306) PDGFRA D842L [plasma membrane] (R-HSA-9674303) PDGFRA V561D [plasma membrane] (R-HSA-9671557) PDGFRA V561A [plasma membrane] (R-HSA-9671968) PDGFRA V536E [plasma membrane] (R-HSA-9671964) PDGFRA V536M [plasma membrane] (R-HSA-9676950) p-11Y PDGFRA D842V [plasma membrane] (R-HSA-9671979) p-11Y PDGFRA D846Y [plasma membrane] (R-HSA-9672009) p-11Y PDGFRA D842del [plasma membrane] (R-HSA-9671998) p-11Y PDGFRA D843_844del [plasma membrane] (R-HSA-9672001) p-11Y PDGFRA D842_I843delinsV [plasma membrane] (R-HSA-9671991) p-11Y PDGFRA D843_846del [plasma membrane] (R-HSA-9672007) p-11Y PDGFRA D842Y [plasma membrane] (R-HSA-9671982) p-11Y PDGFRA D842_H845del [plasma membrane] (R-HSA-9671989) p-11Y PDGFRA D842_D846del [plasma membrane] (R-HSA-9671986) p-10Y PDGFRA Y849C [plasma membrane] (R-HSA-9671977) p-11Y PDGFRA D843_845del [plasma membrane] (R-HSA-9672003) p-11Y PDGFRA N848K [plasma membrane] (R-HSA-9672015) p-11Y PDGFRA D842L dimer [plasma membrane] (R-HSA-9674313) p-11Y PDGFRA D846V [plasma membrane] (R-HSA-9674316) p-11Y PDGFRA V536E [plasma membrane] (R-HSA-9672018) p-11Y PDGFRA V536M [plasma membrane] (R-HSA-9676956) p-11Y PDGFRA V561D [plasma membrane] (R-HSA-9672025) p-11Y PDGFRA V561A [plasma membrane] (R-HSA-9672021) PDGFRA [plasma membrane] (R-HSA-186794) p-11Y-PDGFRA [plasma membrane] (R-HSA-186806)	0.544	2

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