Reactome | Potassium voltage-gated channels (beta cell, closed) [plasma membrane]

Potassium voltage-gated channels (beta cell, closed)

Stable Identifier

R-HSA-381655

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Summation

Human pancreatic beta cells contain Kv2.1, Kv3.2, Kv6.2, and Kv9.3 voltage gated potassium channels. The channels are closed in a resting beta and channels open in response to depolarization. Open channels counteract the effect of closed ATP-gated potassium channels and thereby end stimulation of insulin secretion .

Participants

members

Participant Of

output

Potassium voltage-gated channels close in reponse to PKA

Inferred To

Homologues of KCNC2 [plasma membrane] (Caenorhabditis elegans)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Bos taurus)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Canis familiaris)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Danio rerio)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Drosophila melanogaster)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Gallus gallus)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Mus musculus)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Rattus norvegicus)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Sus scrofa)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Taeniopygia guttata)

Potassium voltage-gated channels (beta cell, open) [plasma membrane] (Xenopus tropicalis)