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Go!
PAPPA [extracellular region]
Stable Identifier
R-HSA-381405
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
PAPP-A, PAPP1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)
PAAP-A proteolyzes IGF:IGFBP4 (Homo sapiens)
PAPPA,PAPPA2 [extracellular region] (Homo sapiens)
PAPPA [extracellular region] (Homo sapiens)
PAPP-A2 proteolyzes IGF:IGFBP5:ALS (Homo sapiens)
PAPPA,PAPPA2 [extracellular region] (Homo sapiens)
PAPPA [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13219 PAPPA
Gene Names
PAPPA
Chain
signal peptide:1-22, propeptide:23-81, chain:82-1627
Reference Genes
BioGPS Gene:5069 PAPPA
COSMIC (genes):PAPPA PAPPA
CTD Gene:5069 PAPPA
dbSNP Gene:5069 PAPPA
ENSEMBL:ENSG00000182752 PAPPA
HGNC:8602 PAPPA
KEGG:hsa:5069 PAPPA
Monarch:5069 PAPPA
NCBI Gene:5069 PAPPA
OMIM:176385 PAPPA
UCSC:Q13219 PAPPA
Reference Transcript
RefSeq:NM_002581.4 PAPPA
Other Identifiers
11727014_at
11727015_s_at
11727016_s_at
11727017_s_at
11727018_s_at
11744843_s_at
11749508_a_at
11754579_at
1559400_PM_s_at
1559400_s_at
17088462
201981_PM_at
201981_at
201982_PM_s_at
201982_s_at
224940_PM_s_at
224940_s_at
224941_PM_at
224941_at
224942_PM_at
224942_at
228128_PM_x_at
228128_x_at
3186502
3186503
3186504
3186505
3186506
3186507
3186522
3186532
3186533
3186536
3186540
3186542
3186556
3186557
3186572
3186573
3186592
3186593
3186594
3186595
3186597
3186603
3186605
3186607
3186608
3186614
3186620
3186623
3186626
3186629
3186635
3186636
3186637
3186638
3186639
3186640
3186641
3186642
3186643
3186644
3186645
3186646
32549_at
45332_r_at
49040_at
5069
8157487
A_14_P107528
A_14_P131961
A_14_P201299
A_23_P216742
A_23_P351270
A_33_P3599591
GE59054
GO:0003824
GO:0004175
GO:0004222
GO:0005515
GO:0005576
GO:0005615
GO:0006508
GO:0007166
GO:0007565
GO:0008237
GO:0008270
GO:0016787
GO:0022414
GO:0030163
GO:0032354
GO:0046872
GO:0071548
GO:0140096
HMNXSV003014734
Hs.250655.4.S1_3p_at
Hs.250655.4.S2_3p_a_at
Hs.250655.5.S1_3p_at
Hs.75874.0.A2_3p_at
Hs2.423154.1.S1_3p_s_at
ILMN_1721770
PH_hs_0030277
PH_hs_0030443
TC09000593.hg
TC09002209.hg
U28727_at
g4505606_3p_a_at
Participates
as a member of
PAPPA,PAPPA2 [extracellular region] (Homo sapiens)
Inferred To
Pappa [extracellular region]
(Rattus norvegicus)
pappa [extracellular region]
(Xenopus tropicalis)
pappaa [extracellular region]
(Danio rerio)
PAPPA [extracellular region]
(Bos taurus)
PAPPA [extracellular region]
(Canis familiaris)
PAPPA [extracellular region]
(Gallus gallus)
PAPPA [extracellular region]
(Mus musculus)
PAPPA [extracellular region]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000328252
,
ENSP00000330658
,
ENSG00000182752
OpenTargets
ENSG00000182752
IntEnz
3.4.24.79
GeneCards
PAPPA
HPA
ENSG00000182752-PAPPA
PRO
Q13219
Pharos - Targets
Q13219
PDB
7Y5Q
,
8HGG
,
7Y5N
,
8A7E
,
8A7D
,
8D8O
,
7UFG
,
8HGH
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