Reactome | XBP1-2 [nucleoplasm]

Stable Identifier

R-HSA-381096

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

XBP1(S), XBP1 isoform 2, XBP-1S

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P17861-2 XBP1

Gene Names

XBP1, TREB5, XBP2

Participates

as an output of

This entity regulates

Positively

Cross References

RefSeq

NP_001073007.1, NP_005071.2

ENSEMBL

ENST00000216037, ENST00000344347, ENSP00000216037, ENSP00000343155, ENSG00000100219

OpenTargets

ENSG00000100219

GeneCards

XBP1

HPA

ENSG00000100219-XBP1

ZINC - Substances

XBP1_HUMAN

ZINC target

P17861

PRO

P17861

Pharos - Targets

P17861

PDB

6R6G, 6R5Q, 6R6P, 6R7Q

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P18850 ATF6	7	ATF6 [endoplasmic reticulum membrane] (R-HSA-381222) ATF6 [Golgi membrane] (R-HSA-381000) ATF6(1-419) [Golgi membrane] (R-HSA-420815) ATF6(1-380) [cytosol] (R-HSA-381075) ATF6(380-419) [Golgi membrane] (R-HSA-420817) ATF6(420-670) [Golgi membrane] (R-HSA-420814) ATF6(1-380) [nucleoplasm] (R-HSA-381211)	0.623	4
UniProt:Q16665 HIF1A	7	HIF1A [nucleoplasm] (R-HSA-1234135) HIF1A [cytosol] (R-HSA-1234102) p-Y565-HIF1A [cytosol] (R-HSA-8857584) p-Y565,S797-HIF1A [cytosol] (R-HSA-9634700) HN-HIF1A [cytosol] (R-HSA-1234110) 2xHP-HIF1A [cytosol] (R-HSA-1234131) 2xHP-HIF1A [nucleoplasm] (R-HSA-1234105)	0.591	3

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