Reactome | loading of Serotonin in synaptic vesicles

loading of Serotonin in synaptic vesicles

Stable Identifier

R-HSA-380586

Type

Reaction [transition]

Species

Homo sapiens

Compartment

clathrin-sculpted monoamine transport vesicle lumen, cytosol

ReviewStatus

5/5

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loading of Serotonin in synaptic vesicles

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Serotonin is loaded into the clathrin sculpted monoamine transport vesicle by vesicular monoamine transporter (Johnssom 1998, Henry et al. 1994).

Literature References

PubMed ID	Title	Journal	Year
7823026	Biochemistry and molecular biology of the vesicular monoamine transporter from chromaffin granules Henry, JP, Botton, D, Sagne, C, Isambert, MF, Desnos, C, Blanchard, V, Raisman-Vozari, R, Krejci, E, Massoulie, J, Gasnier, B	J. Exp. Biol.	1994
2892215	Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport Johnson, RG	Physiol. Rev.	1988
23363473	Brain dopamine-serotonin vesicular transport disease and its treatment Rilstone, JJ, Alkhater, RA, Minassian, BA	N. Engl. J. Med.	2013