loading of Serotonin in synaptic vesicles

Stable Identifier
R-HSA-380586
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Serotonin is loaded into the clathrin sculpted monoamine transport vesicle by vesicular monoamine transporter (Johnssom 1998, Henry et al. 1994).

Literature References
PubMed ID Title Journal Year
2892215 Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport

Johnson, RG

Physiol. Rev. 1988
7823026 Biochemistry and molecular biology of the vesicular monoamine transporter from chromaffin granules

Henry, JP, Botton, D, Sagne, C, Isambert, MF, Desnos, C, Blanchard, V, Raisman-Vozari, R, Krejci, E, Massoulie, J, Gasnier, B

J. Exp. Biol. 1994
23363473 Brain dopamine-serotonin vesicular transport disease and its treatment

Rilstone, JJ, Alkhater, RA, Minassian, BA

N. Engl. J. Med. 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
monoamine transmembrane transporter activity of SLC18A2 [clathrin-sculpted monoamine transport vesicle membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created