Reactome | Loss of proteins required for interphase microtubule organization from the centrosome

Loss of proteins required for interphase microtubule organization from the centrosome

Stable Identifier

R-HSA-380284

Type

Pathway

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Loss of proteins required for interphase microtubule organization from the centrosome

Click the image above or here to open this pathway in the Pathway Browser

In addition to recruiting proteins and complexes necessary for increased microtubule nucleation, centrosomal maturation involves the loss of proteins involved in interphase microtubule organization and centrosome cohesion (Casenghi et al., 2003; Mayor et al., 2002).

Literature References

PubMed ID	Title	Journal	Year
12140259	The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles Hacker, U, Mayor, T, Nigg, EA, Stierhof, YD	J Cell Sci	2002
12852856	Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation Duncan, PI, Nigg, EA, Weinhart, U, Casenghi, M, Körner, R, Meraldi, P	Dev Cell	2003