valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate

Stable Identifier
R-HSA-380042
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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VARS (cytosolic valyl tRNA synthetase) catalyzes the reaction of valine, tRNA(Val), and ATP to form Val-tRNA(Val), AMP, and pyrophosphate. The enzyme is a class I tRNA synthetase (Vilalta et al. 1993).
Literature References
PubMed ID Title Journal Year
8428657 Cloning, sequencing and expression of a cDNA encoding mammalian valyl-tRNA synthetase

Donovan, D, Vogeli, G, Yang, DC, Wood, L, Vilalta, A

Gene 1993
Participants
Participates
Catalyst Activity

valine-tRNA ligase activity of VARS [cytosol]

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Created
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