arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate

Stable Identifier
R-HSA-379993
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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RARS (cytosolic arginyl tRNA synthetase) catalyzes the reaction of arginine, tRNA(Arg), and ATP to form Arg-tRNA(Arg), AMP, and pyrophosphate. The enzyme, a class I tRNA synthetase, is a monomer found in the cell as a component of the mutienzyme aminoacyl-tRNA synthetase complex (Ling et al. 2005).

Literature References
PubMed ID Title Journal Year
16055448 The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex

Ling, C, Yao, YN, Zheng, YG, Wei, H, Wang, L, Wu, XF, Wang, ED

J Biol Chem 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
arginine-tRNA ligase activity of aminoacyl-tRNA synthetase multienzyme complex [cytosol]
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Activity
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