aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate

Stable Identifier
R-HSA-379867
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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DARS (cytosolic aspartyl tRNA synthetase) catalyzes the reaction of aspartate, tRNA(Asp), and ATP to form Asp-tRNA(Asp), AMP, and pyrophosphate. The enzyme, a class II tRNA synthetase, is a homodimer found in the cell as a component of the mutienzyme aminoacyl-tRNA synthetase complex (Escalante and Yang 1993).

Literature References
Participants
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Catalyst Activity
Catalyst Activity
Title
aspartate-tRNA ligase activity of aminoacyl-tRNA synthetase multienzyme complex [cytosol]
Physical Entity
Activity
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