Reactome | AIMP1(1-312) [cytosol]

AIMP1(1-312) [cytosol]

Stable Identifier

R-HSA-379609

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

SCYE1, Multisynthetase complex auxiliary component p43

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q12904 AIMP1

Gene Names

AIMP1, EMAP2, SCYE1

Chain

initiator methionine:1, chain:2-312, chain:147-312

Reference Genes

BioGPS Gene:9255 AIMP1

COSMIC (genes):AIMP1 AIMP1

CTD Gene:9255 AIMP1

dbSNP Gene:9255 AIMP1

ENSEMBL:ENSG00000164022 AIMP1

HGNC:10648 AIMP1

KEGG:hsa:9255 AIMP1

Monarch:9255 AIMP1

NCBI Gene:9255 AIMP1

OMIM:603605 AIMP1

UCSC:Q12904 AIMP1

Reference Transcript

Participates

as a component of

Inferred To

AIMP1(1-312) [cytosol] (Dictyostelium discoideum)

AIMP1(1-312) [cytosol] (Rattus norvegicus)

AIMP1 [cytosol] (Canis familiaris)

AIMP1 [cytosol] (Drosophila melanogaster)

AIMP1 [cytosol] (Gallus gallus)

AIMP1 [cytosol] (Sus scrofa)

Aimp1 [cytosol] (Mus musculus)

SCYE1 [cytosol] (Bos taurus)

Cross References

RefSeq

NP_004748.2, XP_016864325.1, XP_016864324.1, XP_054207221.1, NP_001135888.2, XP_047272366.1, NP_001135887.1

OpenTargets

ENSG00000164022

ENSEMBL

ENSP00000500159, ENSP00000500732, ENSP00000500668, ENSP00000499921, ENST00000673123, ENSP00000350699, ENST00000672341, ENST00000672285, ENSP00000499850, ENST00000671960, ENST00000672337, ENST00000672328, ENST00000672911, ENSG00000164022, ENST00000673018, ENSP00000500170, ENSP00000500794, ENSP00000500025, ENSP00000500620, ENST00000358008, ENST00000671868

HPA

ENSG00000164022-AIMP1

GeneCards

AIMP1

PRO

Q12904

Pharos - Targets

Q12904

Orphanet

AIMP1

GlyGen

Q12904

PDB

8J9S, 1E7Z, 8ONG, 1FL0, 4R3Z, 1EUJ

HMDB Protein

HMDBP13586

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.706	16
UniProt:P47897 QARS1	2	QARS [cytosol] (R-HSA-379615) QARS [mitochondrial matrix] (R-HSA-379592)	0.527	3

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