Reactome | HARS2 [mitochondrial matrix]

HARS2 [mitochondrial matrix]

Stable Identifier

R-HSA-379581

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Histidyl-tRNA synthetase 2

Locations in the PathwayBrowser for interactor UniProt:Q9Y478 PRKAB1

Expand all

External Reference Information

External Reference

UniProt:P49590 HARS2

Gene Names

HARS2, HARSL, HARSR, HO3

Chain

transit peptide:1-33, chain:34-506

Reference Genes

BioGPS Gene:23438 HARS2

COSMIC (genes):HARS2 HARS2

CTD Gene:23438 HARS2

dbSNP Gene:23438 HARS2

ENSEMBL:ENSG00000112855 HARS2

HGNC:4817 HARS2

Monarch:23438 HARS2

NCBI Gene:23438 HARS2

OMIM:600783 HARS2

UCSC:P49590 HARS2

Reference Transcript

Other Identifiers

11717486_a_at

11751295_a_at

16990166

209252_PM_at

209252_at

23438

2832053

2832054

2832055

2832056

2832057

2832058

2832059

2832060

2832061

2832062

2832064

2832065

2832066

2832067

2832068

2832069

2832070

2832071

2832072

2832073

2832074

2832075

2832076

2832082

2832083

2832084

2832085

37240_at

8108603

A_14_P105484

A_14_P121707

A_23_P41588

GE58987

GO:0003723

GO:0003824

GO:0004812

GO:0004821

GO:0005515

GO:0005524

GO:0005737

GO:0005739

GO:0005759

GO:0005829

GO:0006399

GO:0006412

GO:0006418

GO:0006427

GO:0006520

GO:0016874

GO:0042802

GO:0043226

GO:0140098

HMNXSV003004114

ILMN_1715113

PH_hs_0025247

TC05000732.hg

U18937_at

g899108_3p_at

Cross References

ENSEMBL

ENST00000645749, ENSP00000494296, ENSP00000230771, ENST00000508522, ENSP00000423616, ENST00000230771

OpenTargets

ENSG00000112855

HPA

ENSG00000112855-HARS2

PRO

P49590

Pharos - Targets

P49590

Orphanet

HARS2

HMDB Protein

HMDBP00642

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P10809 HSPD1	6	HSPD1(1-573) [cytosol] (R-HSA-1267989) HSPD1(1-573) [mitochondrial intermembrane space] (R-HSA-1267963) HSPD1(1-26) [mitochondrial matrix] (R-HSA-8986171) HSPD1(1-573) [mitochondrial inner membrane] (R-HSA-1299442) HSPD1 [mitochondrial inner membrane] (R-HSA-1299455) HSPD1 [mitochondrial matrix] (R-HSA-1299448)	0.615	5
UniProt:Q6RW13 AGTRAP	2	AGTRAP(1-159)-BRAF(288-545) fusion [cytosol] (R-HSA-6802262) AGTRAP(1-159)-p-BRAF(288-545) fusion [cytosol] (R-HSA-6802511)	0.556	3
UniProt:O75251 NDUFS7	1	NDUFS7 [mitochondrial matrix] (R-HSA-6788521)	0.527	2
UniProt:Q7Z2W9 MRPL21	1	MRPL21 [mitochondrial inner membrane] (R-HSA-5368231)	0.527	3
UniProt:Q9UK85 DKKL1			0.527	2
UniProt:P58557 YBEY			0.527	2
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.527	2
UniProt:Q96KS9 F167A			0.527	2
UniProt:Q07954 LRP1	2	LRP1 [endocytic vesicle membrane] (R-HSA-2230981) LRP1 [plasma membrane] (R-HSA-1454844)	0.527	2
UniProt:P52815 MRPL12	2	MRPL12 [mitochondrial inner membrane] (R-HSA-5368256) MRPL12 [mitochondrial matrix] (R-HSA-9839674)	0.527	3
UniProt:Q8TBP5 F174A			0.527	3
UniProt:Q9Y478 PRKAB1	2	PRKAB1 [cytosol] (R-HSA-380968) PRKAB1 [nucleoplasm] (R-HSA-2151199)	0.527	2
UniProt:P21912 SDHB	2	SDHB [mitochondrial inner membrane] (R-HSA-70985) SDHB [mitochondrial matrix] (R-HSA-9854983)	0.527	2
UniProt:Q9UQV4 LAMP3			0.527	3
UniProt:P12081 HARS1	1	HARS [cytosol] (R-HSA-379554)	0.527	2
UniProt:P04591-PRO_0000038593 GAG			0.462	3

Cite Us!